ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025
Long-term survival outcomes in young-onset colorectal cancer: A population-based cohort study.
Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Differences in quality of life between early onset colorectal cancer patients compared to older patients: a qualitative study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Long-term survival outcomes in young-onset colorectal cancer: A population-based cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
- Safety of fruquintinib in Chinese patients with colorectal cancer: an age subgroup analysis from a phase IV real-world clinical practice study.Therapeutic advances in medical oncology · 2025Article
- Socioeconomic Disadvantage, but Not Remote Location, Is Associated With Poorer Survival After Resection of Colon Cancer in Queensland Patients: A Population-Based Retrospective Cohort Study.ANZ journal of surgeryArticle
- What Is the Evidence Base Regarding Early Onset Colorectal Cancer in Australia and New Zealand? A Scoping Review.ANZ journal of surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimLong-term survival outcomes in young-onset colorectal cancer patients are contradictory and inconsistent. Some studies report overall survival to be significantly superior compared with older adults, while others report worse survival. Worldwide, the incidence of young-onset colorectal cancer has, alarmingly, nearly doubled since the 1990s, in stark contrast to that in those over 50 years of age. Long-term survival in young-onset colorectal cancer has not been explored in the Australian population. The aim of this study was to investigate cancer-specific and overall survival up to 10 years.
methodThis was a retrospective population-based cohort study. All colorectal cancer diagnoses between 2001 and 2020 in the state of Queensland, Australia were reviewed. Young-onset colorectal cancer (20-49 years) was compared with late-onset colorectal cancer (50 years+).
resultsThere were 52 697 adults diagnosed with colorectal cancer in Queensland. Young-onset colorectal cancer accounted for 7.7% of these. Young-onset colorectal cancer had a greater proportion of Stage III and IV disease than the late-onset group (66% vs. 59%, p < 0.001). Despite this, young-onset colorectal cancer had statistically significant improved overall survival at all time points to 10 years (p < 0.001). Stage-for-stage cancer-specific survival to 10 years was superior in all stages in young-onset colorectal cancer (p < 0.001).
conclusionBoth stage-for-stage cancer-specific and overall survival were superior in young-onset colorectal cancer compared with those aged 50 years and above, up to 10 years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.