Evidence map›Paper›PMID 41979898›Full record

ArticleThe Journal of clinical investigation2026

The EGFR regulates bacterial clearance in cystic fibrosis airway neutrophils.

Lawrence W Rasmussen, Deepali Luthra, Diego Moncada-Giraldo, Crystal Lewis, Yixel M Soto-Vazquez, Zhuo Li, Buqu Hu, Brian S Dobosh, Delores A Stacks, Jonathan L Koff and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of clinical investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lawrence W RasmussenDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Deepali LuthraDepartment of Pediatrics, Emory University, Atlanta, Georgia, USA.
Diego Moncada-GiraldoDepartment of Pediatrics, Emory University, Atlanta, Georgia, USA.
Crystal LewisDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Yixel M Soto-VazquezDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Zhuo LiDepartment of Pediatrics, Emory University, Atlanta, Georgia, USA.
Buqu HuDepartment of Medicine, Yale University, New Haven, Connecticut, USA.
Brian S DoboshDepartment of Pediatrics, Emory University, Atlanta, Georgia, USA.
Delores A StacksDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jonathan L KoffDepartment of Medicine, Yale University, New Haven, Connecticut, USA.
Amit GaggarDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Rabindra TirouvanziamDepartment of Pediatrics, Emory University, Atlanta, Georgia, USA.
Camilla MargaroliDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidermal growth factor receptor influences how airway neutrophils clear bacteria in cystic fibrosis, revealing a novel mechanism in neutrophil biology.

Indexed as

Cystic FibrosisErbB ReceptorsNeutrophilsAnimalsHumansEGFR protein, humanErbB ReceptorsBacterial infectionsGrowth factorsImmunologyNeutrophilsPulmonology

Identifiers

PMID41979898
PMCPMC13262706

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.