Long-Term Durability of Stylet-Driven Leads for Left Bundle Branch Area Pacing.

Hao Liu, Wesley Alleman, Keith Victorine, Cody Ledbetter, Robert Shaw

Abstract read

In one paragraph

Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao LiuAbbott Laboratories, Sylmar, CA, 91342, USA. hao.liu2@abbott.com.ORCID http://orcid.org/0000-0002-5152-0845

Wesley AllemanAbbott Laboratories, Sylmar, CA, 91342, USA.

Keith VictorineAbbott Laboratories, Sylmar, CA, 91342, USA.

Cody LedbetterAbbott Laboratories, Sylmar, CA, 91342, USA.

Robert ShawAbbott Laboratories, Sylmar, CA, 91342, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeQuantify the long-term mechanical durability of Abbott stylet-driven leads for left bundle branch area pacing (LBBAP) using a combination of computational modeling and fatigue bench test.

methodsIntracardiac lead curvatures were simulated in a 3D computational heart model across a range of lead implant scenarios and cardiac electro-mechanical scenarios over a complete cardiac cycle to determine the range of induced stresses. Safety factor was determined using the bending curvature and mechanical properties of the conductor. A benchtop fatigue physical test was implemented at higher stress levels, thus lower safety factors, than the computational modeling cohort.

resultsComputer simulation modeling showed that maximum curvature and safety factor (SF) were comparable for LBBA implants (0.06 ± 0.02 mm

conclusionAbbott stylet-driven leads were demonstrated to be safe for LBBAP, even at stresses far exceeding those which may be clinically observed for 400 million cardiac cycles. No differences in long-term safety were observed between LBBAP and traditional pacing locations.

Indexed as

In silico modelingIn vitro bench testingLead durabilityLeft bundle branch area pacingSafety factors

Identifiers

PMID41979869

DOI10.1016/j.hrthm.2019.06.016

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.