Evidence map›Paper›PMID 41979858›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Real-time assessment of inter and intraventricular synchrony in cardiac resynchronization therapy with left bundle branch pacing using ECGi and low-frequency QRS analysis.

Clara Sales-Belles, Ana Mincholé, Mercedes Cabrera-Ramos, Jorge Melero-Polo, Esther Pueyo, Javier Ramos Maqueda

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Clara Sales-BellesBSICoS Group, Aragon Institute of Engineering Research, IIS Aragón, University of Zaragoza, Zaragoza, Spain.
Ana MincholéBSICoS Group, Aragon Institute of Engineering Research, IIS Aragón, University of Zaragoza, Zaragoza, Spain.
Mercedes Cabrera-RamosArrhythmias Unit, Cardiology Department, Lozano Blesa Clinical University Hospital, Zaragoza, Spain.
Jorge Melero-PoloArrhythmias Unit, Cardiology Department, Lozano Blesa Clinical University Hospital, Zaragoza, Spain.
Esther PueyoBSICoS Group, Aragon Institute of Engineering Research, IIS Aragón, University of Zaragoza, Zaragoza, Spain.
Javier Ramos MaquedaArrhythmias Unit, Cardiology Department, Lozano Blesa Clinical University Hospital, Zaragoza, Spain. javierramos@unizar.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLeft bundle branch pacing (LBBP) is an alternative to conventional biventricular pacing for cardiac resynchronization therapy (CRT).

methodsA 76-year-old male was referred for CRT via left bundle branch pacing (LBBP). We present the real-time characterization of the transition from intrinsic left bundle branch block (LBBB) to sequential pacing modalities: right ventricular septal pacing (RVSP), left ventricular septal pacing (LVSP), and finally LBBP. Epicardial activation maps from electrocardiographic imaging (ECGi) and low-frequency (LF) QRS analysis were used to provide complementary insights into inter- and intraventricular synchrony.

resultsLVSP, LBBP, and anodal capture improved activation compared with baseline, with LBBP achieving the greatest improvements in interventricular and LV intraventricular synchrony despite higher RV dispersion.

conclusionThese findings highlight ECGi and LF QRS as valuable tools to guide CRT.

Indexed as

cardiac resynchronization therapyECGelectrocardiographic imagingLeft bundle branch pacing

Identifiers

PMID41979858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.