Evidence map›Paper›PMID 41979708›Full record

ArticleSleep & breathing = Schlaf & Atmung2026

Slow miniscrew-assisted palatal expansion: a clinical approach for long-term skeletal stability and enhanced nasal airway function.

Rana Kiziltekin Cimen, Choon Bong Lee, Huy Young Kim, Stanley Yung-Chuan Liu, Hwa Sung Chae, Christine Hong

Abstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rana Kiziltekin CimenDepartment of Orofacial Sciences, University of California, San Francisco, School of Dentistry, San Francisco, CA, USA.
Choon Bong LeeDental Clinic Director, Gounmiso Orthodontic Clinic, Bucheon, South Korea.
Huy Young KimDepartment of Family Medicine, Ajou University Hospital, Suwon, South Korea.
Stanley Yung-Chuan LiuDepartment of Oral & Maxillofacial Surgery, Nova Southeastern University, Fort Lauderdale, FL, USA.
Hwa Sung ChaeDepartment of Orthodontics, Institute of Oral Health Science, Ajou University School of Medicine, Suwon, South Korea. hwasungchae@ajou.ac.kr.
Christine HongDepartment of Orofacial Sciences, University of California, San Francisco, School of Dentistry, San Francisco, CA, USA. yeumin.hong@ucsf.edu.ORCID http://orcid.org/0000-0002-9123-7737

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess whether slow-activation miniscrew-assisted palatal expansion (MAPE) improves skeletal dimensions, nasal airflow and patient-reported symptoms in maxillary transverse hypoplasia (MTH).

methodsIn this prospective cohort, 45 subjects underwent slow-activation MAPE and were stratified as pediatric (< 18y; n = 22) and adult (≥ 18y; n = 23). Outcomes were collected at baseline (T0), post-expansion (T1), post-orthodontics (T2) and 1-year retention (T3). CBCT quantified zygomatic and nasal widths and internal nasal valve (INV) area/angle and intermolar widths. Peak nasal/oral inspiratory flows (PNIF/POIF) were measured at T0–T3. Patient-reported outcomes included a 23-item binary questionnaire and the Epworth Sleepiness Scale (ESS).

resultsZygomatic and nasal widths and INV area/angle increased in both cohorts (all p < 0.001), with larger INV changes in pediatrics (p < 0.05). PNIF increased and remained above baseline at T3 (p < 0.001), while morning mouth dryness upon waking and daytime mouth breathing decreased (both p < 0.01). Sleepiness outcomes were not uniformly improved. Using Johns ESS categories, from T0 to T3, 67% of pediatric participants shifted to lower-normal and 33% remained higher-normal, whereas all adults remained higher-normal. Using a two-group threshold informed by Korean validation (ESS ≥ 8 vs. < 8), 35% were ≥ 8 at baseline; at T3, all pediatric participants and 25% of adults who were ≥ 8 shifted to < 8, while 75% remained ≥ 8.

conclusionsSlow-activation MAPE was associated with skeletal and nasal complex widening, INV enlargement, and sustained PNIF improvement, but daytime sleepiness improved inconsistently, particularly in adults. Without polysomnography, findings reflect changes in upper-airway physiology and symptoms rather than definitive changes in sleep-disordered breathing severity.

Indexed as

Bone ScrewsMaxillaPalatal Expansion TechniqueAdolescentAdultChildFemaleHumansMaleProspective StudiesYoung AdultCone-beam computed tomography (CBCT)Maxillary transverse hypoplasia (MTH)Miniscrew-assisted palatal expander (MAPE)Nasal airway functionPeak nasal inspiratory flow (PNIF)

Identifiers

PMID41979708
PMCPMC13079501

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.