Evidence map›Paper›PMID 41979285›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2026

The impact of on-field rehabilitation on return to play and ACL re-injury risk after ACL reconstruction in football (soccer) players: A study on 401 consecutive cases.

Francesco Della Villa, Filippo Picinini, Stefano Di Paolo, Alberto Scavone, Daniele Caminati, Jacopo Gamberini, Matthew Buckthorpe

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Francesco Della VillaIsokinetic Medical Group, Education and Research Department, FIFA Medical Centre of Excellence, Bologna, Italy.ORCID https://orcid.org/0000-0001-9379-6666
Filippo PicininiIsokinetic Medical Group, Education and Research Department, FIFA Medical Centre of Excellence, Bologna, Italy.
Stefano Di PaoloIsokinetic Medical Group, Education and Research Department, FIFA Medical Centre of Excellence, Bologna, Italy.ORCID https://orcid.org/0000-0002-1761-7352
Alberto ScavoneIsokinetic Medical Group, Education and Research Department, FIFA Medical Centre of Excellence, Bologna, Italy.
Daniele CaminatiIsokinetic Medical Group, Education and Research Department, FIFA Medical Centre of Excellence, Bologna, Italy.
Jacopo GamberiniIsokinetic Medical Group, Education and Research Department, FIFA Medical Centre of Excellence, Bologna, Italy.
Matthew BuckthorpeIsokinetic Medical Group, Education and Research Department, FIFA Medical Centre of Excellence, Bologna, Italy.ORCID https://orcid.org/0000-0002-4925-4031

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeExamine the association between preoperative, intraoperative and postoperative variables, including on-field rehabilitation (OFR) participation and return to play (RTP) rates and re-injury risk in a large cohort of 11-a-side football (soccer) players after anterior cruciate ligament reconstruction (ACLR).

methodsData from 401 male football players who underwent primary ACLR were retrospectively analysed. All players completed a standardised rehabilitation protocol, involving a period of OFR. Participants were stratified by competitive level (professionals and amateurs), and between-group differences in RTP and re-injury outcomes were documented. The association between preoperative, intraoperative and postoperative variables for each outcome was assessed using logistic regressions, controlling for competitive level.

resultsMedian follow-up time was 40.6 months post-ACLR. Eighty-four percent of players RTP at their pre-injury competitive level, with professionals (88%) and amateurs (83%) returning in 5.9 ± 2.1 and 6.9 ± 3.2 months, respectively. Greater OFR volume (odds ratio [OR], 1.06; 95% confidence interval [CI], 1.00-1.12; p = 0.034) and weekly frequency (OR, 1.53; 95% CI, 1.00-1.07; p = 0.014) were associated with increased RTP likelihood. High OFR compliance was associated with higher odds of RTP (OR = 2.62, p = 0.003), in which 91% of compliant players RTP at their pre-injury competitive level. Forty-two players (10%) sustained a second ACL injury (20 ipsilateral and 22 contralateral). OFR variables were not significantly associated with overall second ACL re-injury risk. In an exploratory subgroup analysis of young (<20 years old) players, OFR compliance was associated with lower odds of ipsilateral re-injury (OR = 0.23, p = 0.041).

conclusionACLR football players in our cohort had high RTP (88%) and low ACL re-injury risk (10%). Greater exposure to OFR, particularly higher volume and weekly frequency, was associated with an increased likelihood of RTP. No association was observed between OFR compliance and overall second ACL injury risk, although in young players, greater OFR compliance was associated with a reduction in ipsilateral ACL re-injury. LEVEL OF EVIDENCE: Level IV.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionAthletic InjuriesKnee InjuriesReinjuriesReturn to SportSoccerAdolescentAdultHumansMaleRetrospective StudiesRisk FactorsYoung AdultACL injurycontextinjury aetiologyinjury preventiontiming

Identifiers

PMID41979285
PMCPMC13266922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.