Evidence map›Paper›PMID 41979076›Full record

ArticleVirulence2026

Isolation and characterization of a red panda amdoparvovirus causing fatal respiratory disease: Identification of VP2-S447 as a key determinant of acute lung injury.

Liulu Yang, Linchong Nie, Hongjie Ren, Houjing He, Hao Yuan, Zipeng Yang, Kunmei Yang, Wenhao Li, Xianghe Wang, Xiu-Xiang Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Liulu YangGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Linchong NieGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Hongjie RenGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Houjing HeGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Hao YuanGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zipeng YangGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Kunmei YangGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Wenhao LiGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xianghe WangGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xiu-Xiang ZhangCollege of Agriculture, South China Agricultural University, Guangzhou, China.
Yining SongGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zi-Guo YuanGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-3592-4743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surveillance and control of wildlife-borne pathogens are essential for preventing cross-species transmission. Ongoing diversity in Aleutian virus infection among small carnivoran has expanded host range and promoted viral adaptation, leading to the emergence of previously unknown mutations as the virus spreads across geographic and species boundaries. In this study, we report the first isolation and characterization of a highly pathogenic red panda amdoparvovirus (Designated as RpAPV-Gd1) from a fatal case in a captive red panda (

Indexed as

Acute Lung InjuryAiluridaeCapsid ProteinsParvoviridae InfectionsAmino Acid SubstitutionAnimalsCell LineChinaFemaleGenome, ViralHumansLungMiceMice, Inbred BALB CPhylogenyReverse GeneticsCapsid Proteinsacute lung injuryAmdoparvovirusred panda amdoparvovirusreverse geneticsS447VP2 protein

Identifiers

PMID41979076
PMCPMC13114132

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.