Evidence map›Paper›PMID 41978904›Full record

ArticleRegenerative biomaterials2026

A multifunctional EGCG/Si nanohybrid-coated 3D-printed porous scaffold for bone defect repair.

Shiqi Xiao, Lin Qi, Jiacheng Wei, Huan Liu, Sheng Ding, Ju Chen, Jin Yang, Hua Lin, Dianxiang Lu

Abstract read
In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shiqi XiaoClinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu 610081, China.
Lin QiDepartment of Criminal Science and Technology, Sichuan Police College, Luzhou 646000, China.
Jiacheng WeiSchool of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, China.
Huan LiuSchool of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, China.
Sheng DingClinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu 610081, China.
Ju ChenClinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu 610081, China.
Jin YangClinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu 610081, China.
Hua LinDepartment of Stomatology, The First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, China.
Dianxiang LuClinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu 610081, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Besides enhancing osteogenesis and angiogenesis, designing multifunctional scaffolds with immunomodulatory capabilities offers a promising strategy for managing bone defects. Herein, a 3D-printed scaffold modified with inorganic silicon (Si) ions and the polyphenol epigallocatechin gallate (EGCG) was constructed as an immunomodulatory biocomposite with coupled angiogenic and osteogenic activity to enhance bone regeneration. Through phenol-amine chemistry and electrostatic layer-by-layer deposition, a nanohybrid EGCG/Si coating was fabricated on the poly(lactic-co-glycolic acid) scaffold surface. Our

Indexed as

3D printingbone regenerationEGCG/Si nanohybrid coatingmultifunctional scaffolds

Identifiers

PMID41978904
PMCPMC13070653

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.