SynthesisPeerJ2026
Improving respiratory muscle strength in patients with multiple sclerosis through respiratory muscle training: a systematic review and meta-analysis.
Synthesis in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Multiple sclerosis (MS) has a high incidence and can occur at all ages, and respiratory dysfunction is a leading cause of death among the complications of MS. Respiratory muscle training (RMT) is often used to help MS patients improve their respiratory function, but the specific impact of RMT has not been clearly elucidated. The present meta-analysis aims to evaluate the impact of RMT on MS patients. Methods: We looked up PubMed, Cochrane Library, Embase, Web of Science, and PEDro with the query "respiratory muscle training" AND "multiple sclerosis". The cutoff was January 6, 2026. After screening, eligible randomized controlled clinical trials were analyzed to calculate the standardized mean differences (SMDs) and 95% confidence intervals (CI) of the following metrics regarding RMT intervention: maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), forced vital capacity (FVC), forced expiratory volume in one second (FEV Results: A total of 370 articles were retrieved, and eight remained after rigorous screening. The eight trials included a total of 249 patients. Patients undergoing RMT exhibited significant improvements in MEP (SMD = 0.42, 95% CI [0.09-0.76], Conclusions: Respiratory muscle training can improve respiratory muscle strength and the lung function in MS patients.
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Registered trials
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