ReviewMaedica2026
The Impact of Enhanced Recovery after Surgery Protocol on Health-Related Quality of Life Following Colorectal Surgery: a Literature Review.
Review in Maedica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Enhanced recovery after surgery (ERAS) protocols are widely adopted in colorectal surgery to reduce postoperative complications, length of stay and costs, but their impact on health-related quality of life (HRQoL) is less clear. Methods: A literature review was conducted through PubMed (MEDLINE) to December 2024, including randomized trials and observational studies evaluating ERAS implementation in colorectal surgery with HRQoL as primary or secondary outcome, using validated or clearly described HRQoL instruments. Results: Fifteen studies met the inclusion criteria, encompassing heterogeneous patient populations, procedures and ERAS pathways. Early randomized trials generally reported no significant differences in global HRQoL scores between ERAS and standard care, although ERAS cohorts frequently showed faster recovery of instrumental activities of daily living, earlier return to leisure or work and shorter hospitalization without increased complications. More recent studies, including larger prospective series, increasingly demonstrated higher HRQoL scores in ERAS groups across multiple domains using instruments such as EORTC QLQ-CR38 and WHOQOL-BREF, and identified non-ERAS perioperative care as an independent negative prognostic factor for long-term HRQoL improvement. No study reported detrimental effects of ERAS on HRQoL. Conclusions: The available evidence, although limited and methodologically heterogeneous, suggests that ERAS protocols in colorectal surgery have a neutral to beneficial impact on HRQoL, while maintaining well-established clinical advantages. Future research should include rigorously designed studies with HRQoL as a primary endpoint, standardized ERAS components and consistent use of validated HRQoL tools to allow more definitive recommendations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.