Evidence map›Paper›PMID 41978845›Full record

ReviewMaedica2026

Current Approach in Acute Biliary Pancreatitis - a Narrative Review.

Ana-Laura Dima, Ana-Laura Manda, Dragos Virgil Davitoiu, Catalin Viorel Lutic, Daniel Iulian Voiculescu

Abstract readReview
In one paragraph

Review in Maedica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana-Laura Dima"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Ana-Laura MandaUniversity Emergency Hospital Bucharest, Romania.
Dragos Virgil Davitoiu"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Catalin Viorel LuticUniversity Emergency Hospital Bucharest, Romania.
Daniel Iulian Voiculescu"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute biliary pancreatitis (ABP), caused by gallstone migration, is the most common form of acute pancreatitis. Although overall mortality has decreased due to therapeutic advances, severe forms still carry a mortality rate of 10-30%. Methodology: This narrative review analyses guidelines, randomized trials and meta-analyses published between 2021-2025 that were selected according to PRISMA 2020 criteria. Results: Severity assessment relies on clinical scores (BISAP, CTSI) and 48-hour CRP levels, while artificial intelligence models such as EASY-APP may improve early risk stratification. Abdominal ultrasound remains the first-line diagnostic tool, with MRCP and elevated ALT supporting biliary aetiology. Current management favours moderate fluid resuscitation with Ringer lactate and early enteral nutrition, while avoiding total parenteral nutrition. Pain control may include NSAIDs or opioids, with epidural analgesia considered in severe cases. Antibiotic therapy is reserved for infected necrosis or cholangitis. Endoscopic retrograde cholecysto-pancreatography (ERCP) is selectively indicated mainly for therapeutic purposes. Early cholecystectomy during the same admission is the standard for mild ABP, whereas moderate and severe forms require a step-up approach. Conclusions: Modern management of ABP is oriented to more physiological approaches, emphasizes individualized care, minimally invasive strategies and physiological support, as well as a tailored approach to the support and interventional components, contributing to improved outcomes and reduced mortality in specialized centres.

Indexed as

acute biliary pancreatitischolecystectomyERCPstep-up approach

Identifiers

PMID41978845
PMCPMC13061446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.