Evidence map›Paper›PMID 41978821›Full record

ArticleOpen forum infectious diseases2026

Interdisciplinary Pediatric Long-COVID Care: A Descriptive Study of Interventions and Health-Related Quality of Life.

David W Miller, Samuel N Rodgers-Melnick, Nada Tharwat Deraz, Jeffery A Dusek, Tracy L Segall, Amy M Edwards

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David W MillerConnor Whole Health, University Hospitals of Cleveland, Cleveland, Ohio, USA.
Samuel N Rodgers-MelnickConnor Whole Health, University Hospitals of Cleveland, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-0886-253X
Nada Tharwat DerazSchool of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0007-9622-5261
Jeffery A DusekSchool of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Tracy L SegallConnor Whole Health, University Hospitals of Cleveland, Cleveland, Ohio, USA.
Amy M EdwardsSchool of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0006-3287-1507

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Data on pediatric long-COVID is limited to descriptive reports of symptom prevalence and incidence, with few studies describing integrative care or including patient-reported quality of life. This study describes demographic, clinical, symptom severity, and intervention characteristics within a pediatric long-COVID clinic involving collaboration between infectious disease and integrative medicine physicians. Methods: Clinical data were extracted from the electronic health records for patients aged 4-25 with long-COVID seen within this clinic. A subset of patients completed validated PROs of wellbeing, fatigue, sleep-related impairment and disturbance, depression, and anxiety. Results: A cohort of 214 patients (mean age 14.7, 61% female, 83% White) were seen between March 2021 and June 2023, with 39.7% providing Pediatric Quality of Life Inventory (PedsQL) and 30.3% providing Patient-Reported Outcomes Measurement Information System (PROMIS) measures. Common documented conditions included fatigue (85%), headache (75.2%), dizziness (64.5%), anxiety (62.1%), and nausea (59.3%). Common interventions included diet changes (81.8%), pacing (65.9%), sleep hygiene (61.2%), and other self-care techniques (46.7%). The long-COVID cohort reported elevated PROMIS sleep disturbance (61.79), sleep-related impairment (63.9), anxiety (58.1), and depression (58.1) as well as PedsQL total fatigue (40.19). These scores were more severe than national norms as well as compared with other pediatric chronic disease cohorts (eg, chronic pain, cancer, sickle cell disease, autism). Conclusions: Pediatric patients with long-COVID report high symptom burden. This study describes patient characteristics, care delivered and provides a novel description of symptom severity. Future research among more diverse populations is needed to evaluate outcomes of this integrative care.

Indexed as

COVID-19fatiguelong-COVIDpediatrics

Identifiers

PMID41978821
PMCPMC13070613

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.