Evidence map›Paper›PMID 41978632›Full record

ReviewSAGE open medicine2026

Epidemiology of cancer-related pain in Africa: A systematic review and meta-analysis of studies from 2001 to 2024.

Molla Amsalu Tadesse, Getachew Mekete Deress, Gezahagn Demsu Gedefaw, Eniyew Assimie Alemu, Abere Gebru Abuhay, Asnake Tadesse Abate, Tsehayu Melak Siyoum, Daniel Getaneh Damtie, Agernesh Dereje Misker, Habtie Bantider Wubet and 6 more

Abstract readReview
In one paragraph

Review in SAGE open medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Molla Amsalu TadesseDepartment of Anesthesia, Asrat Woldeyes Health Sciences Campus, Debre Berhan University, Debre Berhan, Ethiopia.ORCID https://orcid.org/0009-0004-0266-5708
Getachew Mekete DeressDepartment of Anesthesia, School of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID https://orcid.org/0009-0006-1463-3222
Gezahagn Demsu GedefawDepartment of Neonatal Health Nursing, School of Nursing, College of Medicine and Health Sciences, and Comprehensive Specialized Hospital, University of Gondar, Gondar, Northwest Ethiopia.
Eniyew Assimie AlemuDepartment of Anesthesia, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.ORCID https://orcid.org/0009-0007-3250-101X
Abere Gebru AbuhayDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Northwest Ethiopia.
Asnake Tadesse AbateDepartment of Neonatal Health Nursing, School of Nursing, College of Medicine and Health Sciences, and Comprehensive Specialized Hospital, University of Gondar, Gondar, Northwest Ethiopia.
Tsehayu Melak SiyoumDepartment of Neonatal Health Nursing, School of Nursing, College of Medicine and Health Sciences, and Comprehensive Specialized Hospital, University of Gondar, Gondar, Northwest Ethiopia.
Daniel Getaneh DamtieDepartment of Anesthesia, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Agernesh Dereje MiskerDepartment of Midwifery, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Habtie Bantider WubetDepartment of Anesthesia, School of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Walelign Asmie AfeworkDepartment of Adult Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Amanu Addis MelesewDepartment of Adult Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Negesse Zurbachew GobezieDepartment of Anesthesia, School of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID https://orcid.org/0000-0002-8401-309X
Biruk DemissieDepartment of Environmental health, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Begizew Yimenu MekuriawDepartment of Midwifery, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID https://orcid.org/0009-0009-0400-3827
Temesgen Birlie AsmareDepartment of Anesthesia, School of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID https://orcid.org/0009-0008-0462-8299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pain is a common symptom at cancer diagnosis and often worsens with treatment and disease progression. Comprehensive evidence on its prevalence and severity in Africa remains limited. Objectives: This systematic review and meta-analysis aimed to estimate the prevalence and severity of cancer-related pain among adult cancer patients in Africa using available evidence. Methods: Google Scholar, PubMed, and the Cochrane Library were searched for articles that reported the prevalence of pain in cancer patients in African countries. The methodological quality of included studies was assessed using a quality assessment tool for prevalence studies, and the certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework. Pooled estimates of the prevalence and severity of cancer-related pain were calculated. Study heterogeneity was assessed using I², while sensitivity analyses were performed to test the robustness of the findings. Results: This meta-analysis included 23 studies conducted in African nations. In all included studies, 5378 patients with cancer at various stages of anticancer treatment were included. The pooled prevalence of pain was 76% (95% CI: 71%-81%, Conclusion: More than three-quarters of patients suffer from cancer-related pain, with a substantial proportion experiencing moderate-to-severe levels with moderate certainty. Considerable variability exists in pain prevalence and severity across studies and regions of Africa. As a result, findings should be interpreted with caution. Improving access to analgesics may help alleviate pain and enhance quality of life for cancer patients.

Indexed as

Africacancercancer painepidemiologyneoplasmpainprevalence

Identifiers

PMID41978632
PMCPMC13070181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.