Evidence map›Paper›PMID 41978095›Full record

ArticleNutrients2026

Structural Characterization and Anti-Colitis Mechanisms of

Jiaman Xu, Junna Zheng, Wukang Ke, Yu Qiu, Lu Zhang, Chenxi Wu, Xiaoxi Zhang, Daozong Xia, Fenfen Li

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Immune-Enhancing Effects ofCurrent issues in molecular biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaman XuSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Junna ZhengSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID 0009-0001-8637-0509
Wukang KeSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yu QiuSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Lu ZhangSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Chenxi WuSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xiaoxi ZhangSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Daozong XiaSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID 0000-0002-7902-5002
Fenfen LiSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.

Funding

2024 Zhejiang Chinese Medicine University Cultivation Plan for Top Innovative Talents of Postgraduates 2024YJSBJ010China Postdoctoral Science Foundation 2024M762961National Natural Science Foundation of China 82204726Research Project of Zhejiang Chinese Medical University 2023RCZXZK40
6 · The paper itself

Abstract

background

methodsA homogeneous polysaccharide, PSP-1b (57.45 kDa), was isolated from the rhizomes of PS via ion-exchange and gel filtration chromatography and structurally characterized using chromatographic and spectroscopic methods. In vivo, its effects were evaluated in a dextran sulfate sodium (DSS)-induced mouse model of UC, while in vitro mechanisms were explored using macrophages stimulated with lipopolysaccharide (LPS) and neutrophil extracellular traps (NETs).

resultsPSP-1b was identified as a neutral polysaccharide with minimal branching. Its primary structural backbone was largely composed of →4)-β-D-Gal

conclusionsPSP-1b as a promising candidate for functional foods or therapeutic agents targeting inflammatory bowel disease.

Indexed as

Anti-Inflammatory AgentsColitis, UlcerativeExtracellular TrapsMacrophagesPolygonatumPolysaccharidesAnimalsDextran SulfateDisease Models, AnimalMaleMiceMice, Inbred C57BLNeutrophilsRAW 264.7 CellsRhizomeSignal TransductionAnti-Inflammatory AgentsDextran SulfatePolysaccharidesinflammationmacrophageneutrophil extracellular trapsPolygonatum sibiricumpolysaccharidestructural characterization

Identifiers

PMID41978095
PMCPMC13074318

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.