Evidence map›Paper›PMID 41977873›Full record

ArticleSensors (Basel, Switzerland)2026

Electrochemical Detection of miR-29a and miR-34a Using AuNPs Immobilized by a Silsesquioxane Polyelectrolyte: Potential Early Alzheimer's Disease Biomarkers Detection.

Amanda Loos Vargas Zinser, Felipe Zahrebelnei, João Paulo Winiarski, Paulo Henrique de Souza Picciani, Karen Wohnrath, Christiana Andrade Pessôa

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amanda Loos Vargas ZinserDepartment of Chemistry, State University of Ponta Grossa, Ponta Grossa CEP 84030-900, PR, Brazil.ORCID 0009-0005-4464-8567
Felipe ZahrebelneiDepartment of Chemistry, State University of Ponta Grossa, Ponta Grossa CEP 84030-900, PR, Brazil.ORCID 0000-0002-6785-9843
João Paulo WiniarskiDepartment of Chemistry, Federal University of Santa Catarina, Florianópolis CEP 88040-900, SC, Brazil.ORCID 0000-0002-5676-3993
Paulo Henrique de Souza PiccianiInstitute of Macromolecules, Federal University of Rio de Janeiro, Rio de Janeiro CEP 21941-901, RJ, Brazil.
Karen WohnrathDepartment of Chemistry, State University of Ponta Grossa, Ponta Grossa CEP 84030-900, PR, Brazil.
Christiana Andrade PessôaDepartment of Chemistry, State University of Ponta Grossa, Ponta Grossa CEP 84030-900, PR, Brazil.ORCID 0000-0001-8973-5908

Funding

Fundação Araucária 22.027.260-5National Council for Scientific and Technological Development 406008/2022-1National Institute of Organic Electronics (INEO) 465572/2014-6
6 · The paper itself

Abstract

Alzheimer's Disease (AD) is the leading cause of dementia worldwide, and early diagnosis is crucial to minimize neurological damage and loss of quality of life. Here, we report an electrochemical biosensor for detecting miRNAs 29a and 34a, potential non-invasive biomarkers associated with AD. The biosensor consisted of a glassy carbon electrode (GCE) modified with a novel nanohybrid of gold nanoparticles stabilized by 3-n-propyl(4-dimethylaminopyridinium) silsesquioxane chloride (AuNPs-Si4DMAP

Indexed as

Alzheimer DiseaseBiosensing TechniquesElectrochemical TechniquesGoldMetal NanoparticlesMicroRNAsOrganosilicon CompoundsBiomarkersDielectric SpectroscopyElectrodesHumansBiomarkersGoldMicroRNAsMIRN29a microRNA, humanMIRN34 microRNA, humanOrganosilicon CompoundsAlzheimer’s diseaseelectrochemical biosensorgold nanoparticlesmiRNA-29amiRNA-34asilsesquioxane

Identifiers

PMID41977873
PMCPMC13074746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.