Evidence map›Paper›PMID 41977580›Full record

ArticlePolymers2026

Multifunctional Konjac Glucomannan Film Tuning by Gallic Acid Functionalization.

Lidia Zasada, Marcin Wekwejt, Marta Michalska-Sionkowska, Anna Michno, Anna Ronowska, Karina Fałkowska, Karolina Dulok, Beata Kaczmarek-Szczepańska

Abstract read
In one paragraph

Article in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lidia ZasadaLaboratory for Functional Polymeric Materials, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Torun, Poland.ORCID 0000-0001-8340-987X
Marcin WekwejtBiomaterials Technology Department, Faculty of Mechanical Engineering and Ship Technology, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland.ORCID 0000-0002-6889-7825
Marta Michalska-SionkowskaDepartment of Environmental Microbiology and Biotechnology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Torun, Poland.ORCID 0000-0002-5851-734X
Anna MichnoDepartment of Clinical Biochemistry, Department of Laboratory Medicine, Medical University of Gdańsk, Skłodowskiej-Curie 3a, 80-210 Gdansk, Poland.
Anna RonowskaDepartment of Clinical Biochemistry, Department of Laboratory Medicine, Medical University of Gdańsk, Skłodowskiej-Curie 3a, 80-210 Gdansk, Poland.ORCID 0000-0001-5715-1211
Karina FałkowskaLaboratory for Functional Polymeric Materials, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Torun, Poland.ORCID 0009-0007-6811-1697
Karolina DulokLaboratory for Functional Polymeric Materials, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Torun, Poland.
Beata Kaczmarek-SzczepańskaLaboratory for Functional Polymeric Materials, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Torun, Poland.ORCID 0000-0002-2563-2376

Funding

National Science Centre UMO-2024/55/D/NZ7/01705Nicolaus Copernicus University EPIBIOMAT Research Group - Epibiocompatible Materials for Medicine and One Health
6 · The paper itself

Abstract

Konjac glucomannan (KG) is a biocompatible polysaccharide with limited functional performance in its native form, motivating modification strategies to enhance its properties. This study investigates the effect of gallic acid (GA) functionalization on the structural, physicochemical, mechanical, antioxidant, and biological properties of KG-based films. FTIR analysis confirmed that GA interacts with KG primarily through non-covalent hydrogen bonding without disrupting the polymer backbone. Modification with GA enabled concentration-dependent tuning of surface energy, roughness, hydration behavior, and water vapor permeability. Mechanical testing revealed a significant increase in stiffness and tensile strength accompanied by reduced elongation at higher GA contents. Antioxidant activity was markedly enhanced even at low GA concentrations. All films exhibited excellent hemocompatibility, while cytocompatibility toward human fibroblasts depended on GA content. Optical analysis indicated moderate color changes without severe discoloration. Overall, GA functionalization effectively improves the functional performance of KG films while preserving polymer integrity. Hence, GA-modified KG films as promising candidates for biomedical applications (like wound dressing) requiring antioxidant activity, controlled hydration, and biocompatibility.

Indexed as

functionalizationgallic acidkonjac glucomannanpacking materialswound dressing

Identifiers

PMID41977580
PMCPMC13074227

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.