Evidence map›Paper›PMID 41977409›Full record

ArticleInternational journal of molecular sciences2026

Interference of Immunosuppressive Therapies with Cellular Antimicrobial Activity Against

Sara Blanco-Conde, Miriam Retuerto-Guerrero, Ramiro López-Medrano, Cristina López-Cadenas, Santiago Vivas-Alegre, Elizabeth de Freitas-González, Nuria López-Morán, Octavio Miguel Rivero-Lezcano

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara Blanco-CondeServicio Análisis Clínicos, Complejo Hospitalario de Vigo, 36213 Vigo, Pontevedra, Spain.
Miriam Retuerto-GuerreroServicio de Reumatología, Complejo Asistencial Universitario de León, Gerencia Regional de Salud de Castilla y León (SACYL), Altos de Nava, s/n, 24071 León, Spain.ORCID 0000-0003-0248-657X
Ramiro López-MedranoServicio de Microbiología Clínica, Complejo Asistencial Universitario de León, Gerencia Regional de Salud de Castilla y León (SACYL), Altos de Nava, s/n, 24071 León, Spain.
Cristina López-CadenasPharmacology, Department of Biomedical Sciences, Veterinary Faculty, Institute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0001-6229-9560
Santiago Vivas-AlegreServicio de Aparato Digestivo, Complejo Asistencial Universitario de León, Gerencia Regional de Salud de Castilla y León (SACYL), Altos de Nava, s/n, 24071 León, Spain.
Elizabeth de Freitas-GonzálezServicio de Neumología, Complejo Asistencial Universitario de León, Gerencia Regional de Salud de Castilla y León (SACYL), Altos de Nava, s/n, 24071 León, Spain.
Nuria López-MoránLaboratorio de Hematología, Complejo Asistencial Universitario de León, Gerencia Regional de Salud de Castilla y León (SACYL), Altos de Nava, s/n, 24071 León, Spain.
Octavio Miguel Rivero-LezcanoUnidad de Investigación, Complejo Asistencial Universitario de León, Gerencia Regional de Salud de Castilla y León (SACYL), Altos de Nava, s/n, 24071 León, Spain.ORCID 0000-0002-8793-0731

Funding

Consejería de Sanidad, Gerencia Regional de Salud de la Junta de Castilla y León GRS 2720/A1/2023
6 · The paper itself

Abstract

Immunosuppressive therapies increase the risk of infection, but there is little information regarding their effects on cellular antimycobacterial activity. In this context, the aim was to evaluate in vitro the impact of commonly used immunosuppressive drugs on the ability of peripheral blood mononuclear cells (PBMCs), neutrophils (polymorphonuclear cells, PMNs), and monocyte-derived macrophages (MDMs) to control

Indexed as

Immunosuppressive AgentsMycobacterium abscessusBiofilmsEverolimusHumansLeflunomideLeukocytes, MononuclearMacrophagesMethotrexateMycophenolic AcidNeutrophilsTacrolimusEverolimusImmunosuppressive AgentsLeflunomideMethotrexateMycophenolic AcidTacrolimusbiofilmchemokinesleflunomidemacrophagesmethotrexateMycobacterium abscessusneutrophilsPBMCprednisolone

Identifiers

PMID41977409
PMCPMC13073738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.