Evidence map›Paper›PMID 41977320›Full record

ArticleInternational journal of molecular sciences2026

Polyfunctionalized

Mireia Toledano-Pinedo, Alicia Porro-Pérez, Linda Schäker-Hübner, Daniel Diez-Iriepa, Isabel Iriepa, Agata Siwek, Małgorzata Wolak, Grzegorz Satała, Andrzej J Bojarski, Agata Doroz-Płonka and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Mireia Toledano-PinedoInstitute of General Organic Chemistry (CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.
Alicia Porro-PérezInstitute of General Organic Chemistry (CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0002-8310-1549
Linda Schäker-HübnerPharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.
Daniel Diez-IriepaInstitute of General Organic Chemistry (CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.
Isabel IriepaDepartamento de Química Orgánica y Química Inorgánica, Instituto de Investigación Química "Andrés M. del Río" (IQAR), Universidad de Alcalá, 28805 Alcalá de Henares, Spain.ORCID 0000-0003-3475-9624
Agata SiwekDepartment of Pharmacobiology, Faculty of Pharmacy, Medical College, Jagiellonian University, 9 Medyczna St., 30-688 Krakow, Poland.
Małgorzata WolakDepartment of Pharmacobiology, Faculty of Pharmacy, Medical College, Jagiellonian University, 9 Medyczna St., 30-688 Krakow, Poland.
Grzegorz SatałaMaj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Krakow, Poland.
Andrzej J BojarskiMaj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Krakow, Poland.ORCID 0000-0003-1417-6333
Agata Doroz-PłonkaDepartment of Technology and Biotechnology of Drugs, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland.
Jadwiga HandzlikDepartment of Technology and Biotechnology of Drugs, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland.ORCID 0000-0002-3674-3581
Justyna GodyńDepartment of Physicochemical Drug Analysis, Faculty of Pharmacy, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland.ORCID 0000-0002-0295-2772
Patrick DallemagneUniversité de Caen Normandie, Normandie University, CERMN UR4258, F-14000 Caen, France.ORCID 0000-0002-4845-615X
Christophe RochaisUniversité de Caen Normandie, Normandie University, CERMN UR4258, F-14000 Caen, France.ORCID 0000-0001-7996-2082
Audrey DavisUniversité de Caen Normandie, Normandie University, CERMN UR4258, Druid Platform, F-14000 Caen, France.ORCID 0000-0002-0157-2380
Marc SinceUniversité de Caen Normandie, Normandie University, CERMN UR4258, Druid Platform, F-14000 Caen, France.ORCID 0000-0003-3984-5812
Belén PérezDepartment of Pharmacology, Therapeutic and Toxicology, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.ORCID 0000-0001-5801-1704
Aina Bellver-SanchisPharmacology Section, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Neuroscience, Universitat de Barcelona (NeuroUB), Av. Joan XXIII 27-31, 08028 Barcelona, Spain.ORCID 0000-0001-9890-753X
Alba IrisarriPharmacology Section, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Neuroscience, Universitat de Barcelona (NeuroUB), Av. Joan XXIII 27-31, 08028 Barcelona, Spain.ORCID 0000-0002-5850-5058
Mercè PallàsPharmacology Section, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Neuroscience, Universitat de Barcelona (NeuroUB), Av. Joan XXIII 27-31, 08028 Barcelona, Spain.ORCID 0000-0003-3095-4254
Cristina Solana-ManriqueDepartamento de Genética, Facultad CC Biológicas, Universidad de Valencia, 46100 Burjassot, Spain.
Francisco López-MuñozFaculty of Health Sciences-HM Hospitals, Camilo José Cela University, 28692 Madrid, Spain.ORCID 0000-0002-5188-6038
Lhassane IsmailiLaboratoire de Recherches Intégratives en Neurosciences et Psychologie Cognitive de Besançon, Groupe Chimie Médicinale, Université de Franche-Comté, INSERM, UMR 1322 LINC, F-25000 Besançon, France.ORCID 0000-0002-6013-3150
Christian Griñán-FerréPharmacology Section, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Neuroscience, Universitat de Barcelona (NeuroUB), Av. Joan XXIII 27-31, 08028 Barcelona, Spain.ORCID 0000-0002-5424-9130
Nuria ParicioDepartamento de Genética, Facultad CC Biológicas, Universidad de Valencia, 46100 Burjassot, Spain.ORCID 0000-0001-7193-2532
Finn K. HansenPharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.ORCID 0000-0001-9765-5975
Anna WięckowskaDepartment of Physicochemical Drug Analysis, Faculty of Pharmacy, Medical College, Jagiellonian University, 9 Medyczna Street, 30-688 Krakow, Poland.ORCID 0000-0003-2549-170X
José Marco-ContellesInstitute of General Organic Chemistry (CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.

Funding

AEI (Government of Spain PID2019-105813RB-C21
6 · The paper itself

Abstract

Herein, we have identified the polyfunctionalized 1-(phenylsulfonyl)-1

Indexed as

AcrylamidesEpigenesis, GeneticIndolesNeuroprotective AgentsParkinson DiseaseAnimalsCaenorhabditis elegansDisease Models, AnimalHumansOxidative StressAcrylamidesIndolesNeuroprotective Agents5-HT6 receptorBiological evaluationChE enzymesDrosophila in vivo modelsMTP150neurodegenerative diseasesParkinson’s diseasesynthesis

Identifiers

PMID41977320
PMCPMC13073873

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.