Evidence map›Paper›PMID 41977253›Full record

ArticleInternational journal of molecular sciences2026

Identification of a Prognostic Gene Signature for Chemoresistance Prediction in Lung Adenocarcinoma by Screening Mitochondrial Metabolism Gene Sets.

Binbin Tan, Jinxu Yang, Xibao Zhao, Shanshan Liu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Binbin TanDepartment of Pharmacology, Shenzhen University Medical School, Shenzhen 518055, China.ORCID 0000-0001-7034-9732
Jinxu YangDepartment of Pharmacology, Shenzhen University Medical School, Shenzhen 518055, China.
Xibao ZhaoDepartment of Pharmacology, Shenzhen University Medical School, Shenzhen 518055, China.
Shanshan LiuDepartment of Pharmacology, Shenzhen University Medical School, Shenzhen 518055, China.ORCID 0009-0007-1283-4458

Funding

the National Natural Science Foundation of China 32470930the National Natural Science Foundation of China 82273485the Natural Science Foundation of Guangdong Province 2022A1515010598the Natural Science Foundation of Guangdong Province 2024A1515012851the Stable Support Project of Shenzhen 20231120113237002the Stable Support Project of Shenzhen 20231120193941001
6 · The paper itself

Abstract

Chemoresistance is a major challenge in lung adenocarcinoma (LUAD) treatment and is associated with mitochondrial metabolism. Using publicly available LUAD transcriptome data, we established a five-gene prognostic signature (

Indexed as

Adenocarcinoma of LungDrug Resistance, NeoplasmLung NeoplasmsMitochondriaAnimalsAntineoplastic AgentsCell Line, TumorCell ProliferationCisplatinGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMiceMolecular Docking SimulationPrognosisTranscriptomeAntineoplastic AgentsCisplatinchemoresistancelung adenocarcinomamitochondrial metabolismmolecular docking

Identifiers

PMID41977253
PMCPMC13073725

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.