Evidence map›Paper›PMID 41977185›Full record

ArticleInternational journal of molecular sciences2026

Distinct and Overlapping Neuroprotective Efficacy of Silk Lutein and Sericin-Derived Oligopeptides from Yellow Silk Cocoons in Rodent Models of A

Pornnarin Taepavarapruk, Virakboth Prum, Manote Sutheerawattananonda

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pornnarin TaepavaraprukDepartment of Physiology, Faculty of Medical Science, Naresuan University, Phitsanulok 65000, Thailand.
Virakboth PrumSchool of Food Technology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Manote SutheerawattananondaSchool of Food Technology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.

Funding

Agricultural Research Development Agency CRP6105022920
6 · The paper itself

Abstract

Yellow silk cocoons of Bombyx mori provide two distinct bioactive classes: the carotenoid silk lutein (SL) and sericin-derived oligopeptides (SDOs). Their comparative efficacy and mechanisms in promoting cognitive health remain uncharacterized. This study compared the neuroprotective and cognitive-enhancing effects of SL and SDOs through chronic oral administration in two rodent models: an amyloid-beta (A

Indexed as

Amyloid beta-PeptidesCognitive DysfunctionLuteinNeuroprotective AgentsOligopeptidesSericinsSilkAgingAnimalsApoptosisBombyxCognitive EnhancementDisease Models, AnimalFemaleHippocampusLong-Term PotentiationAmyloid beta-PeptidesLuteinNeuroprotective AgentsOligopeptidesPeptide FragmentsSericinsSilkbrain agingcognitive declinemulti-target silk bioactivessericin-derived oligopeptidessilk luteinsynaptic plasticity

Identifiers

PMID41977185
PMCPMC13072934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.