Evidence map›Paper›PMID 41977163›Full record

ReviewInternational journal of molecular sciences2026

Human Transglutaminases: Updated Insights into Activation Mechanisms, Allosteric Regulation and Disease.

Pablo Moya-Garrido, Laura P Cano-Gómez, Beatriz Ibarra-Molero, Raquel Godoy-Ruiz, Encarnación Medina-Carmona

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pablo Moya-GarridoDepartamento de Química Física, Facultad de Ciencias, Unidad de Excelencia de Química Aplicada a Biomedicina y Medioambiente (UEQ), Universidad de Granada, 18071 Granada, Spain.
Laura P Cano-GómezDepartamento de Química Física, Facultad de Ciencias, Unidad de Excelencia de Química Aplicada a Biomedicina y Medioambiente (UEQ), Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-0372-7550
Beatriz Ibarra-MoleroDepartamento de Química Física, Facultad de Ciencias, Unidad de Excelencia de Química Aplicada a Biomedicina y Medioambiente (UEQ), Universidad de Granada, 18071 Granada, Spain.
Raquel Godoy-RuizDepartment of Biochemistry, Molecular Biology and Immunology, School of Medicine, University of Malaga, 29010 Malaga, Spain.ORCID 0000-0003-4569-0781
Encarnación Medina-CarmonaDepartamento de Química Física, Facultad de Ciencias, Unidad de Excelencia de Química Aplicada a Biomedicina y Medioambiente (UEQ), Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0001-5600-7648

Funding

Consejería de Universidad, Investigación e Innovación EXP-144-UGR23Ministerio de Ciencia, Innovación y Universidades PID 2023-150671OA-I00Ministerio de Ciencia, Innovación y Universidades RYC2021-031155-INational Ataxia Foundation NAF-SMRG-2024-02
6 · The paper itself

Abstract

Human transglutaminases (hTGs) are Ca

Indexed as

TransglutaminasesAllosteric RegulationAnimalsCalciumEnzyme ActivationHumansProtein Processing, Post-TranslationalCalciumTransglutaminasesallosteric regulationautoimmune diseasescalcium bindingconformational dynamicsgenetic disordershuman transglutaminasesprotein crosslinkingrare diseasesstructure–function relationship

Identifiers

PMID41977163
PMCPMC13073648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.