Evidence map›Paper›PMID 41976973›Full record

ReviewJournal of clinical medicine2026

International Guidelines on Conscious Sedation in Pediatric Dentistry: A Comparative Analysis and Evidence Mapping Study.

Carolina Marques, Mafalda Dinis, João Botelho, Vanessa Machado, Luísa Bandeira Lopes

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carolina MarquesEgas Moniz School of Health & Science, Campus Universitário, Quinta da Granja, Caparica, 2829-511 Almada, Portugal.
Mafalda DinisEgas Moniz School of Health & Science, Campus Universitário, Quinta da Granja, Caparica, 2829-511 Almada, Portugal.
João BotelhoEgas Moniz Center for Interdisciplinar Research (CiiEM); Egas Moniz School of Health & Science, Campus Universitário, Quinta da Granja, Caparica, 2829-511 Almada, Portugal.ORCID 0000-0002-1019-8263
Vanessa MachadoEgas Moniz Center for Interdisciplinar Research (CiiEM); Egas Moniz School of Health & Science, Campus Universitário, Quinta da Granja, Caparica, 2829-511 Almada, Portugal.ORCID 0000-0003-2503-260X
Luísa Bandeira LopesEgas Moniz Center for Interdisciplinar Research (CiiEM); Egas Moniz School of Health & Science, Campus Universitário, Quinta da Granja, Caparica, 2829-511 Almada, Portugal.ORCID 0000-0003-4412-7102

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conscious sedation is widely used in pediatric dentistry to manage dental anxiety, behavioral difficulties, and systemic diseases that compromise patient compliance with dental care. Despite its clinical importance, international recommendations vary considerably.

objectiveTo conduct a comparative analysis and evidence mapping of international clinical practice guidelines on conscious sedation in pediatric dentistry.

methodsA comparative guideline analysis and evidence mapping study was performed. Electronic searches were conducted in PubMed (MEDLINE), Scopus, EMBASE, Cochrane Database of Systematic Reviews, Web of Science, LILACS, SciELO, TRIP, and OpenGrey up to December 2023. Guidelines issued by recognized professional or governmental organization addressing conscious sedation in pediatric dentistry were included. Predefined domains were analyzed, including indications, contraindications, pharmacological agents, dosages, routes of administration, monitoring, discharge criteria, and professional training. Data were synthesized descriptively and graphically mapped to illustrate coverage patterns.

resultsTwelve international guidelines were included. Complete convergence (100%) was observed in core safety domains, such as patient assessment, monitoring, and professional training. A high agreement was found for discharge criteria (91.67%) and contraindications (83.33%). However, substantial variability emerged in pharmacological protocols, with only 16.67% of guidelines providing comprehensive drug and dosage descriptions. Routes of administration and emergency equipment recommendations were inconsistently reported, appearing in 66.67% and 50% of guidelines, respectively.

conclusionsAlthough foundational safety principles are consistently addressed, significant heterogeneity persists in pharmacological and procedural recommendations. This variability may contribute to differences in practice and uncertainty among practitioners. Greater international harmonization of guidelines may improve consistency, enhance clinical decision-making, and strengthen patient safety in pediatric dental care. CLINICAL RELEVANCE: Identifying areas of convergence and variability across international guidelines may support the development of more standardized sedation protocols and promote safer evidence-based clinical practice in pediatric dentistry.

Indexed as

behavior managementclinical practice guidelinesconscious sedationnitrous oxidepediatric dentistry

Identifiers

PMID41976973
PMCPMC13072804

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.