Evidence map›Paper›PMID 41976558›Full record

ReviewFoods (Basel, Switzerland)2026

Agri-Food By-Products in Dairy Sector a Review Focused on Phytochemicals, Extraction Methods Health Benefits and Applications.

Roxana Nicoleta Ratu, Florina Stoica, Bianca Andreea Balint, Ionuț Dumitru Veleșcu, Ioana Cristina Crivei, Sebastian-Paul Lucaci, Florin Daniel Lipșa, Gabriela Râpeanu

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Roxana Nicoleta RatuDepartment of Food Technologies, Faculty of Agriculture, "Ion Ionescu de la Brad" Iași University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0000-0001-5637-4376
Florina StoicaDepartment of Pedotechnics, Faculty of Agriculture, "Ion Ionescu de la Brad" Iași University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.
Bianca Andreea BalintDepartment of Food Technologies, Faculty of Agriculture, "Ion Ionescu de la Brad" Iași University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.
Ionuț Dumitru VeleșcuDepartment of Food Technologies, Faculty of Agriculture, "Ion Ionescu de la Brad" Iași University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0009-0009-2313-0063
Ioana Cristina CriveiDepartment of Food Technologies, Faculty of Agriculture, "Ion Ionescu de la Brad" Iași University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0000-0002-3048-5761
Sebastian-Paul LucaciDepartment of Food Technologies, Faculty of Agriculture, "Ion Ionescu de la Brad" Iași University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0009-0003-6989-345X
Florin Daniel LipșaDepartment of Food Technologies, Faculty of Agriculture, "Ion Ionescu de la Brad" Iași University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0000-0002-2127-4225
Gabriela RâpeanuDepartment of Food Science, Food Engineering, Biotechnology and Aquaculture, Faculty of Food Science and Engineering, Dunărea de Jos University of Galati, 800201 Galați, Romania.ORCID 0000-0002-5804-2786

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expansion of the global agri-food industry has led to the generation of large volumes of processing by-products that, although traditionally treated as waste, represent valuable sources of bioactive phytochemicals with potential for sustainable valorisation. This review critically examines the integration of fruit, vegetable, cereal, and dairy processing side streams into functional dairy products. Particular attention is given to recent advances in green and emerging extraction technologies, including ultrasound-assisted extraction, microwave-assisted extraction, and supercritical fluid extraction, with emphasis on their efficiency, environmental performance, and effects on the stability and recovery of phytochemicals. The review also discusses the health-related properties of these bioactive compounds, including antioxidant, anti-inflammatory, and metabolic regulatory effects, in relation to their incorporation into milk, yogurt, cheese, and ice cream matrices. In addition, key barriers to industrial implementation are assessed, including compound stability, sensory constraints, bioavailability, and current regulatory limitations. Beyond direct fortification, the review also considers broader valorisation pathways, such as the biotechnological production of microbial enzymes from agro-industrial biomass, as relevant strategies for supporting circularity. Overall, this review highlights how sustainable extraction approaches and functional dairy innovation can contribute to improving the nutritional value, resource efficiency, and circularity of the dairy sector.

Indexed as

agri-food by-productsbioactive compoundscircular economydairy sectorfunctional dairy productsgreen extraction technologieshealth benefits

Identifiers

PMID41976558
PMCPMC13072995

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.