ArticleFoods (Basel, Switzerland)2026
Integrated Extraction and Structural Engineering of Chitin from Crayfish Shell Waste Using Alkaline Deep Eutectic Solvents Toward Facile Enzymatic Deacetylation.
Shengyu Yang, Qingqing Xiao, Kaige Chen, Haojie Zhang, Jun Cai, Zexin Zhao
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In one paragraphArticle in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
Shengyu YangKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Centre of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei University of Technology, Wuhan 430068, China.ORCID 0009-0004-9568-0420 Qingqing XiaoKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Centre of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei University of Technology, Wuhan 430068, China.
Kaige ChenKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Centre of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei University of Technology, Wuhan 430068, China.
Haojie ZhangKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Centre of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei University of Technology, Wuhan 430068, China.
Jun CaiKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Centre of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei University of Technology, Wuhan 430068, China.
Zexin ZhaoKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Cooperative Innovation Centre of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei University of Technology, Wuhan 430068, China.ORCID 0000-0001-8975-7664 Funding
Collaborative Grant-in-Aid of the HBUT National "111" Center for Cellular Regulation and Molecular Pharmaceutics XBTK-2024006National Natural Science Foundation of China 32302019Open Project Funding of the Key Laboratory of Fermentation Engineering (Ministry of Education) 202509FE23Special Fund for Central Government to Guide Local Science and Technology Development of Hubei Province 2025CSA116
6 · The paper itselfAbstract
Development of green and efficient technologies for valorizing crayfish shell waste is crucial for enhancing industrial value. This study presents an integrated strategy for the extraction and structural engineering of chitin using a novel alkaline deep eutectic solvent (DES) system composed of lysine and monoethanolamine (LysMEA), which enables the simultaneous deproteinization and architectural modification of chitin. Following mild demineralization, the optimized process yielded chitin with 97.1% purity and a high molecular weight of 209.3 kDa. DES demonstrated considerable reusability and decolorization capability. Structural characterization revealed that the LysMEA system effectively engineered the chitin architecture, resulting in lower crystallinity and a larger surface area compared to conventional methods. This engineered structure rendered the chitin highly accessible to enzymes. Consequently, the chitin extracted by LysMEA exhibited superior reactivity, achieving a deacetylation degree of 63.7% when catalyzed by
Indexed as
chitin deacetylasecrayfish shell wastedeep eutectic solventextractionmolecular dynamics simulationstructural engineering
Identifiers
PMID41976453
PMCPMC13073664
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