In one paragraphReview in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Rada MalkoDepartment of Medical and Molecular Genetics, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.ORCID 0000-0001-9486-4499 Harlan E ShannonHerman B Wells Center for Pediatric Research, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.
Erika A DobrotaHerman B Wells Center for Pediatric Research, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.
Keiko E KreklauHerman B Wells Center for Pediatric Research, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.ORCID 0009-0005-9115-5124 Lauren K StevensHerman B Wells Center for Pediatric Research, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.ORCID 0009-0007-7247-2372 Kyle W JacksonDepartment of Pediatrics, Division of Pediatric Hematology/Oncology, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.
M Reza SaadatzadehHerman B Wells Center for Pediatric Research, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.ORCID 0000-0002-7976-7970 Pankita H PandyaDepartment of Medical and Molecular Genetics, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.ORCID 0000-0002-2021-5821 Karen E PollokDepartment of Medical and Molecular Genetics, Indiana University School of Medicine (IUSM), Indianapolis, IN 46202, USA.ORCID 0000-0001-6031-5707 Funding
Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI David W Clapp · 1999 to 2026
$59.3MProject 2: Biomarkers of endothelial dysfunction in pediatric patients receiving high intensity chemotherapy/irradiationP50HD090215 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI RENBARGER, JAMIE L · 2019 to 2020
$1.4MPediatric and Adult Translational Cancer Drug Discovery and Development Training Program (PACT-D3)T32CA272370 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI David W Clapp, Mark R. Kelley · 2023 to 2026
$569kAmerican Cancer Society Institutional Research Grant 16-192-31Department of Defense DOD CA210123Department of Defense DOD WS00780029NCI NIH HHS T32 CA272370NCI/NIH T32 Pediatric and Adult Translational Cancer Drug Discovery and Development Training Program PACT-D3 T32CA272370NICHD/NIH Specialized Centers in Research in Pediatric Developmental Pharmacology P50HD090215NIH/NCI Cancer Center Support Grant to the Indiana University Simon Comprehensive Cancer Center for use of Shared Resource Facilities Preclinical Modeling and Therapeutics, Flow Cytom-etry, and the Center for Medical Genomics P30CA082709
6 · The paper itselfAbstract
The retinoblastoma (RB) protein was the first tumor suppressor discovered and has been extensively studied for its canonical role in cell-cycle regulation. However, RB has broader noncanonical roles in DNA damage repair, chromosomal stability, apoptosis control, lineage commitment, cell differentiation and broad transcriptional regulation. Historically,
Indexed as
cancercell-cycleretinoblastomatargeted therapytherapeutic response
Identifiers
PMID41976397
PMCPMC13072239
What OpenQuestion holds
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