Evidence map›Paper›PMID 41976232›Full record

ArticleMolecules (Basel, Switzerland)2026

Evidence-Based Management of Sickle Cell Disease: Ethnobotanical Survey and Laboratory Validation of Traditional Herbal Recipes.

Marguerite Borive Amani, Mavar Manga Hélène, Mouithys Mickalad Ange, Nsasi Bakiantima Elodie, Ndezu Angirio Rachel, Memvanga Bondo Patrick, Batina Agasa Salomon, Marini Djang'eing'a Roland

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marguerite Borive AmaniDepartment of Galenic Pharmacy and Drug Analysis, Faculty of Pharmaceutical Sciences, University of Kisangani, Kisangani P.O. Box 2012, Democratic Republic of the Congo.
Mavar Manga HélèneDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kisangani, Kisangani P.O. Box 2012, Democratic Republic of the Congo.
Mouithys Mickalad AngeCenter for Oxygen Research and Development-CIRM, University of Liege, 4000 Liège, Belgium.ORCID 0000-0001-9777-3023
Nsasi Bakiantima ElodieDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, University of Kisangani, Kisangani P.O. Box 2012, Democratic Republic of the Congo.
Ndezu Angirio RachelDepartment of Galenic Pharmacy and Drug Analysis, Faculty of Pharmaceutical Sciences, University of Kisangani, Kisangani P.O. Box 2012, Democratic Republic of the Congo.
Memvanga Bondo PatrickCentre de Recherche et d'Innovation Technologique en Environnement et en Sciences de la Santé (CRITESS), Faculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa P.O. Box 212, Democratic Republic of the Congo.ORCID 0000-0003-3201-7803
Batina Agasa SalomonDepartment of Internal Medicine, Faculty of Medicine, University of Kisangani, Kisangani P.O. Box 2012, Democratic Republic of the Congo.
Marini Djang'eing'a RolandDepartment of Galenic Pharmacy and Drug Analysis, Faculty of Pharmaceutical Sciences, University of Kisangani, Kisangani P.O. Box 2012, Democratic Republic of the Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In traditional medicine, laboratory tests are essential tools used to evaluate practices in healthcare that use natural products, particularly when there are few established treatments such as in the case of chronic diseases like sickle cell disease (SCD). SCD is a genetic hemoglobin disorder associated with hemolysis, oxidative stress, inflammation, and vaso-occlusive complications. This study aims to document medicinal plants used in the management of SCD and the traditional practices associated with their use, in order to assess their added value in relation to biological activities relevant to SCD. First, this study carried out an ethnobotanical survey at Kisangani, with 384 participants. A total of 201 respondents, 58% of whom were women, identified 45 medicinal plant species from 30 families. They reported the use of sugar, caramel, ash, and lemon juice as additives in traditional remedies. Based on several criteria,

Indexed as

Anemia, Sickle CellMedicine, TraditionalPlant ExtractsPlant PreparationsPlants, MedicinalAdultAnti-Inflammatory AgentsAntioxidantsEthnobotanyFemaleHibiscusHumansMalePhytotherapySurveys and QuestionnairesAnti-Inflammatory AgentsAntioxidantsPlant ExtractsPlant Preparationsadditivesantioxidantmedicinal plantsmyeloperoxidasesickle cell diseasesoil type

Identifiers

PMID41976232
PMCPMC13074775

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.