Evidence map›Paper›PMID 41976063›Full record

ArticleAnimals : an open access journal from MDPI2026

Genome-Wide Analysis of Copy Number Variation in Vietnamese Local Chickens.

Thuy Thi-Dieu Nguyen, Ana Tzvetkova, Mai Thi-Dieu Bui, Vo-Anh-Khoa Do, Thuy Thi-Ngoc Dinh, Phuong Thanh Nguyen, Andreas Walter Kuss, Mauro Penasa, Filippo Cendron

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thuy Thi-Dieu NguyenDepartment of Animal Biotechnology, Institute of Biology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 11307, Vietnam.ORCID 0000-0001-9128-4712
Ana TzvetkovaInterfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Felix-Hausdorf-Str. 8, 17489 Greifswald, Germany.ORCID 0000-0003-1576-6511
Mai Thi-Dieu BuiDepartment for Promoting Business Cooperation, Faculty of Agronomy, Vietnam National University of Forestry, Dongnai Campus, Trang Bom 76306, Vietnam.
Vo-Anh-Khoa DoDepartment for Promoting Business Cooperation, Faculty of Agronomy, Vietnam National University of Forestry, Dongnai Campus, Trang Bom 76306, Vietnam.ORCID 0000-0002-8257-183X
Thuy Thi-Ngoc DinhDepartment of Animal Biotechnology, Institute of Biology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 11307, Vietnam.
Phuong Thanh NguyenDepartment of Animal Biotechnology, Institute of Biology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Hanoi 11307, Vietnam.ORCID 0000-0002-1451-1317
Andreas Walter KussInterfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Felix-Hausdorf-Str. 8, 17489 Greifswald, Germany.ORCID 0000-0002-9401-4627
Mauro PenasaDepartment of Agronomy, Food, Natural Resources, Animals and Environment, University of Padova, 35020 Legnaro, Italy.ORCID 0000-0001-9984-8738
Filippo CendronDepartment of Agronomy, Food, Natural Resources, Animals and Environment, University of Padova, 35020 Legnaro, Italy.ORCID 0000-0002-8221-7566

Funding

Ministry of Science and Technology of Vietnam NVQG.2021/DT.10Vietnam Academy of Science and Technology (VAST) KHCBSS.02/21-23
6 · The paper itself

Abstract

Copy number variants (CNVs) are large-scale genomic alterations that contribute substantially to genetic diversity and may influence phenotypic variation in livestock. This study investigated the genome-wide CNV landscape of three Vietnamese indigenous chicken breeds. Whole-genome sequencing on the Illumina platform (3-5× coverage) was performed on 24 individuals from Dong Tao (DT), Cay Cum (CC), and Ri (RI) breeds. A total of 1743 CNVs were detected, clustering into 315 copy number variation regions (CNVRs). Most CNVRs were rare, with 31.7% present in only one animal among breeds. Across the genome, 122 unique CNVRs were distributed over 28 chromosomes, predominantly the first five. Losses were the most frequent type (45.9%), followed by gains (39.3%), and mixed events (14.8%). Within these CNVRs, 3633 genes were identified. In DT and RI, CNVR-embedded genes included several candidates, potentially related to adaptability, development, and phenotypic diversification. Notably, DT harbored genes such as

Indexed as

copy number variantDong Taogenomic variationNGSVietnamese indigenous chicken

Identifiers

PMID41976063
PMCPMC13072240

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.