Evidence map›Paper›PMID 41975996›Full record

ArticleAnimals : an open access journal from MDPI2026

CircCOPS8 Inhibits the Proliferation of Buffalo Myoblasts by Binding to IGF2BP3 and Promoting ATR Gene Expression.

Yuting Dou, Ping Sun, Xiangping Cheng, Mengjie Chen, Xinxin Li, Jieping Huang, Zhipeng Li, Qingyou Liu, Deshun Shi, Hui Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuting DouGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Ping SunGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Xiangping ChengGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Mengjie ChenGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Xinxin LiInstitute of Scientific Research, Guangxi University, Nanning 530004, China.
Jieping HuangGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0001-9210-3995
Zhipeng LiGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0003-3190-2253
Qingyou LiuGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0003-3265-540X
Deshun ShiGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Hui LiGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0002-5604-0592
Jian WangGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0001-5443-2675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buffaloes are vital livestock in South-East Asia, attributed to their adaptation to hot and humid climates as well as their capacity to produce high-quality milk and meat. However, the texture of buffalo meat is suboptimal and its slow growth rate restricts the development of the buffalo farming industry. Consequently, studies exploring the key biochemical factors associated with buffalo muscle development have become a research focus. CircRNAs are a class of non-coding RNAs which can function as molecular sponges, participate in protein scaffold formation, and encode short peptides. Previous studies have shown that circRNAs are capable of regulating muscle development; however, relatively few reports have addressed their association with buffalo muscle development. In this study, data from Western blotting and RT-qPCR showed that circCOPS8 significantly enhanced the differentiation of buffalo myoblasts while inhibiting their proliferation (

Indexed as

CircCOPS8CircRNAsIGF2BP3muscle proliferation

Identifiers

PMID41975996
PMCPMC13071993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.