ArticleDiagnostics (Basel, Switzerland)2026
Renal Peripelvic Extramedullary Haematopoiesis in Myelofibrosis: A Rare Imaging Pitfall Assessed by Multimodality Nuclear Imaging.
Article in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Extramedullary haematopoiesis (EMH) refers to haematopoietic proliferation outside the bone marrow, most often arising as a compensatory response to ineffective marrow function in chronic anaemias and myeloid neoplasms, particularly myelofibrosis and other myeloproliferative neoplasms. While the liver and spleen are typical sites, renal involvement remains particularly uncommon and may mimic infiltrative malignancy or infection on cross-sectional imaging. We report a 35-year-old woman with biopsy-proven grade 2 myelofibrosis who presented with constitutional symptoms, namely asthenia, progressive weight loss, and intermittent fever, in the setting of pancytopenia. Contrast-enhanced CT demonstrated bilateral thoracic paravertebral and presacral soft-tissue masses, with left peripelvic/pelvicalyceal infiltration, raising concern for infiltrative malignancy or infection. [
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