Evidence map›Paper›PMID 41975426›Full record

ArticleBMC chemistry2026

First report on electrochemical sensing of ulipristal acetate in pharmaceutical formulations and biological fluids using reduced graphene oxide-CuO nanohybrid based sensors.

Yasmeen A S Hameed, Ahmed Z M Al-Bassam, Omer A Azher, Moneer A Alrashidi, Kaseb D Alanazi, Razan M Snari, Ahmed M Hameed, Nashwa M El-Metwaly

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Article in BMC chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yasmeen A S HameedDepartment of Chemistry, Faculty of Science, Northern Border University, 73222, Arar, Saudi Arabia.
Ahmed Z M Al-BassamDepartment of Postgraduate Affairs, University of Baghdad, Baghdad, Iraq.
Omer A AzherDepartment of Laboratory Medicine, Faculty of Applied Biomedical Sciences, Al-Baha University, Al-Baha, Saudi Arabia.
Moneer A AlrashidiDepartment of Basic Science and Technologies, Applied College, Taibah University, 42353, Madina, Saudi Arabia.
Kaseb D AlanaziDepartment of Chemistry, College of Science, University of Ha'il, 81442, Hail, Saudi Arabia.
Razan M SnariDepartment of Chemistry, Faculty of Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Ahmed M HameedDepartment of Chemistry, Faculty of Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Nashwa M El-MetwalyDepartment of Chemistry, Faculty of Sciences, Umm Al-Qura University, Makkah, Saudi Arabia. n_elmetwaly00@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study illustrated for the first time the construction, characterization, and electroanalytical validation of reduced graphene oxide-copper oxide nanoparticles based screen-printed carbon electrodes (rGO-CuONPs-SPCEs) for sensitive differential pulse voltammetric quantification of ulipristal acetate (ULP) in pharmaceutical and biological samples. The rGO/CuONPs ratio within the nanohybrid was optimized with comprehensive characterization of the morphology and the electroanalytical features of the electrode surface. The fabricated sensors with the optimal composition exhibited enhanced performance towards the oxidation of ULP molecule at 0.72 V with a diffusion-controlled mechanism. Deep and comprehensive molecular orbital and electroanalytical studies sustained oxidation of the terminal nitrogen atom (N2) with the transfer of two electrons/one proton. The illustrated calibration graphs were linear within the ULP concentration ranged from 0.010 to 5.04 µgmL

Indexed as

Biological fluidsDifferential pulse voltammetryMolecular orbital calculationsPharmaceutical formulationsReduced graphene oxide-copper oxide nanoparticles platformUlipristal acetate

Identifiers

PMID41975426
PMCPMC13196222

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