Evidence map›Paper›PMID 41975375›Full record

ArticleBMC oral health2026

The association between sleep quality and postoperative pain after half-impacted mandibular third molar extraction: comparison of three statistical models.

Liwei Hu, Chengzhi Zhao, Ting Wang, Chengyu Xue, Shuangling Wang, Chunlan Liu, Tingting Zhang, Xingfeng Lu, Yubin Cao, Jian Pan

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Liwei Hu *State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Chengzhi Zhao *State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Ting WangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Chengyu XueState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Shuangling WangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Chunlan LiuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Tingting ZhangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Xingfeng LuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China.
Yubin CaoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China. yubin.cao@scu.edu.cn.
Jian PanState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University, No.14, Section 3rd, Renmin Nan Road, Chengdu, Sichuan, 610041, China. jianpancn@scu.edu.cn.

Funding

Research and Develop Program, West China Hospital of Stomatology Sichuan University RD-03-202405Sichuan Science and Technology Program 2023ZYD0110
6 · The paper itself

Abstract

backgroundPain is the common complication after tooth extraction, while the reasons behind it still remains. Insomnia, another prevalent issue, negatively affects physical, mental health, and quality of life. The relations between postoperative pain and insomnia have not been discussed before.

methodsIn this prospective study, we enrolled patients who visited the Department of Oral Surgery, West China Stomatology Hospital of Sichuan University from November 2024 to February 2025 based on inclusion and exclusion criteria. Athens Insomnia Scale (AIS), as an internationally recognized self-rating scale of sleep quality were applied for insomnia evaluation. Visual Analogue Scale (VAS) was applied for postoperative pain measurement. Multiple linear regression was conducted for the analysis of population characteristics and AIS scores. Restricted cubic spline (RCS) logistic regression model, weighted quantile sum (WQS) regression model, and bayesian kernel machine regression (BKMR) model were applied for analyzing interactions among AIS items and postoperative pain.

resultsGender and age are closely to higher AIS scores. Based on RCS logistic regression model analysis, more AIS scores are related to more severe postoperative pain. Based on qgcomp model regression index analysis, AIS-3 and AIS-5 has negative effect on postoperative pain. While other AIS items show positive effects, among which AIS-6 has the biggest effect. Based on BKMR model analysis, AIS-1 and AIS-8 showed a promoting trend in post-tooth extraction pain, while other items had no significant impact on postoperative pain.

conclusionsIn this prospective study, we noticed the importance of the levels and subtypes of insomnia in preventing postoperative pain. Various AIS item could contribute to postoperative pain in different way. Managing sleep conditions could be beneficial for releasing postoperative pain in clinics.

Indexed as

Models, StatisticalMolar, ThirdPostoperative PainSleep Initiation and Maintenance DisordersSleep QualityTooth ExtractionTooth, ImpactedAdultFemaleHumansMalePain MeasurementProspective StudiesYoung AdultAIS scaleInsomniaPostoperative painTooth extraction

Identifiers

PMID41975375
PMCPMC13248310

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