ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Renal ultrasonography findings are associated with urinary tract infection in neonates with asymptomatic hyperbilirubinemia.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study evaluated clinical, laboratory, and ultrasonographic factors associated with UTI in neonates hospitalized for unexplained hyperbilirubinemia. STUDY
designThis retrospective cohort study included 96 neonates hospitalized for unexplained hyperbilirubinemia requiring phototherapy. UTI was defined by pyuria (>5 WBC/high-power field) and growth of a single uropathogen (≥50,000 CFU/mL) from catheterized urine samples. Neonates were classified as UTI-positive (n = 30) or UTI-negative (n = 66). Demographic characteristics, bilirubin levels, inflammatory markers, and renal ultrasonography findings were compared.
resultsUTI was diagnosed in 31.2% of neonates. Bilirubin levels, white blood cell counts, and C- reactive protein concentrations did not differ between groups. Pathological renal ultrasonography findings were significantly more frequent in the UTI group and were independently associated with UTI (odds ratio 4.62; 95% CI 1.39-15.40).
conclusionRenal ultrasonography findings are strongly associated with UTI in hospitalized neonates with unexplained hyperbilirubinemia and may serve as a useful adjunctive evaluation tool in this high-risk population.
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