ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Effects of a respiratory care protocol incorporating less invasive surfactant administration in infants born at 30-34 weeks' gestation.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
10 authors.
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Abstract
objectiveTo evaluate the impact of a respiratory care protocol (RCP) including stepwise escalation of continuous positive airway pressure (CPAP) guided by FiO
methodsWe compared maternal and neonatal variables between cohorts of preterm infants born January 2017-Sept 2018, (pre-RCP) and Oct 2018-Dec 2020 (post-RCP). Infants receiving CPAP for ≥24 h were included and infants intubated at birth were excluded.
resultsCompared to pre-RCP (n = 325), the post-RCP (n = 395) cohort had higher exposure to antenatal steroid, lower median GA, and received higher CPAP in the delivery room, at admission, and before surfactant therapy. Similarly, the need for mechanical ventilation was lower within the first 72 h of life and during the hospital stay in the post -RCP cohort.
conclusionImplementation of an RCP decreased the need for mechanical ventilation in 30-34 weeks' GA infants.
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