Evidence map›Paper›PMID 41975109›Full record

ArticleActa neurochirurgica2026

Selecting the optimal keyhole approach for internal carotid and middle cerebral artery aneurysms. Anatomical comparison of transorbital, lateral supraorbital and minipterional routes with clinical implications.

Alejandra Mosteiro, Marta Codes, Gloria Cabrera, Xavier Montero Mena, Thomaz Topczewski, Hugo Andrade-Barazarte, Ivan Radovanovic, Alberto Prats-Galino, Alberto Di Somma, Joaquim Enseñat and 1 more

Abstract readComparative Study
In one paragraph

Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Alejandra MosteiroDepartament de Cirurgia I Especialitats Medicoquirúrgiques, Universitat de Barcelona (UB), Facultat de Medicina I Ciències de La Salut, Barcelona, Spain.
Marta CodesInstitut Clínic de Neurociències (ICN), Department of Neurological Surgery, Hospital Clínic de Barcelona, Barcelona, Spain.
Gloria CabreraInstitut Clínic de Neurociències (ICN), Department of Neurological Surgery, Hospital Clínic de Barcelona, Barcelona, Spain.
Xavier Montero MenaFaculty of Physics, University of Barcelona, Barcelona, Spain.
Thomaz TopczewskiInstitut Clínic de Neurociències (ICN), Department of Neurological Surgery, Hospital Clínic de Barcelona, Barcelona, Spain.
Hugo Andrade-BarazarteDivision of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Ivan RadovanovicDivision of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Alberto Prats-GalinoDepartament de Cirurgia I Especialitats Medicoquirúrgiques, Universitat de Barcelona (UB), Facultat de Medicina I Ciències de La Salut, Barcelona, Spain.
Alberto Di SommaDepartament de Cirurgia I Especialitats Medicoquirúrgiques, Universitat de Barcelona (UB), Facultat de Medicina I Ciències de La Salut, Barcelona, Spain. adisomma@clinic.cat.
Joaquim EnseñatDepartament de Cirurgia I Especialitats Medicoquirúrgiques, Universitat de Barcelona (UB), Facultat de Medicina I Ciències de La Salut, Barcelona, Spain.
Ramon TornéDepartament de Cirurgia I Especialitats Medicoquirúrgiques, Universitat de Barcelona (UB), Facultat de Medicina I Ciències de La Salut, Barcelona, Spain.

Funding

Instituto de Salud Carlos III PI24/01506
6 · The paper itself

Abstract

purposeAmong the keyhole approaches for the treatment of anterior circulation aneurysms, the minipterional (MPT) and lateral supraorbital (LSO) mini-craniotomies have gained great acceptance. With the recent introduction of the transorbital (TO) route to the Silvian fissure and carotid cistern, an objective analysis is required to stablish general indications and limits to each approach.

methodsFour heads (8 sides) were used for each of the three approaches (TO, LSO, MPT). All specimens underwent a basal CT scan for neuronavigation. Procedures were performed simulating a real surgical scenario, exposing four vascular targets: posterior communicating artery (PCom), internal carotid bifurcation (ICA), M1 segment and bifurcation of the middle cerebral artery (MCA). Surgical freedom (SF) and working angles were calculated at the four vascular targets, and mean differences were compared with Kruskal-Wallis. Transferability of data are demonstrated with three illustrative cases.

resultsThe ICA segments C6-C7, PCom and M1 segment and MCA bifurcation could be exposed ipsilaterally in all specimens and for all three approaches. With the PCom as a target, mean area of SF achieved was 36.19 (27.66) cm

conclusionsOur data supports the addition of a new ventral route - the TO approach - to the already available keyhole routed to the anterior circulation (MTP and LSO). Manoeuvrability analysis contemplates independently four major vascular targets, providing more detailed data to help select the most appropriate approach for each individual case.

Indexed as

Carotid Artery, InternalCraniotomyIntracranial AneurysmMiddle Cerebral ArteryCadaverHumansNeuronavigationOrbitAneurysmsLateral SupraorbitalMinipterionalSurgical freedomTransorbital

Identifiers

PMID41975109
PMCPMC13183721

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.