Evidence map›Paper›PMID 41975093›Full record

ArticleNature microbiology2026

Acetate utilization strategy in chain-elongating bacteria determines butyrate versus medium-chain carboxylate production.

Ian M Gois, Connor M Bowers, Byung-Chul Kim, Robert Flick, Christopher E Lawson

Abstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ian M Gois *Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-0255-8764
Connor M Bowers *Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.
Byung-Chul KimDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-8424-4998
Robert FlickDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.
Christopher E LawsonDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada. chris.lawson@utoronto.ca.ORCID http://orcid.org/0000-0002-3473-1640

Funding

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (Conseil de Recherches en Sciences Naturelles et en Génie du Canada) NSERC-CREATE 528163-2019Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (Conseil de Recherches en Sciences Naturelles et en Génie du Canada) RGPIN-2021-02684
6 · The paper itself

Abstract

Chain-elongating bacteria (CEB) are a unique guild of anaerobes that upcycle organic waste into valuable short- and medium-chain carboxylic acids (MCCAs), enabling a circular bioeconomy. However, the metabolic rules that determine product chain length have remained elusive. Here we combine

Indexed as

AcetatesBacteriaButyratesCarboxylic AcidsCarbon IsotopesCoenzyme A-TransferasesProteomicsSubstrate SpecificityAcetatesButyratesCarbon IsotopesCarboxylic AcidsCoenzyme A-Transferases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.