Evidence map›Paper›PMID 41975082›Full record

ReviewCurrent urology reports2026

Advancements in the Treatment and Management of Voiding Dysfunction in Individuals with Spina Bifida.

Jonathan T Xu, Joshua D Roth

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jonathan T XuDivision of Pediatric Urology, Riley Hospital for Children, Indiana University, 575 Riley Hospital Drive, MSA1, Indianapolis, IN, 46202, USA. jtxu@iu.edu.ORCID http://orcid.org/0000-0001-8893-4286
Joshua D RothDivision of Pediatric Urology, Riley Hospital for Children, Indiana University, 575 Riley Hospital Drive, MSA1, Indianapolis, IN, 46202, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis manuscript aims to provide an overview of the pathophysiology of voiding dysfunction, management goals, and treatment options for individuals with spina bifida in order to better assist providers caring for these patients and their families. RECENT

findingsRecent studies have demonstrated efficacy and safety of beta-3 agonists and onabotulinum toxin A as noninvasive options for management of neurogenic lower urinary tract dysfunction. Studies focusing on patient reported outcomes and health-related quality of life have raised greater awareness of patient goals and socio-environmental factors in the counseling of different treatment options. This review highlights the latest research on the management of voiding dysfunction in patients living with spina bifida. Better understanding of pathophysiology and new developments in non-invasive treatment options have substantially improved long-term durability and outlook for these patients. Future research should aim to identify patient and family goals to better manage expectations and quality of life for this lifelong condition.

Indexed as

Spinal DysraphismUrinary Bladder, NeurogenicAdrenergic beta-3 Receptor AgonistsBotulinum Toxins, Type AHumansQuality of LifeAdrenergic beta-3 Receptor AgonistsBotulinum Toxins, Type Aonabotulinum toxin ABeta-3 agonistIntravesical therapyMyelomeningoceleNeuropathic bladderPatient-reported outcome measuresSpina bifida

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.