Evidence map›Paper›PMID 41975076›Full record

ArticlePediatric research2026

A novel urine collection device for accurate urinary measurements in neonates and pre-continent infants.

Sylvia P Nauta, Lieke A E A Corbeek, Miranda van Berkel, Christine Ten Hove, Petra A van Setten, Joost G J Hoenderop

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sylvia P NautaRadboud University Medical Center, Amalia Children's Hospital, Department of Pediatric Endocrinology, Nijmegen, the Netherlands.ORCID http://orcid.org/0000-0003-0484-5556
Lieke A E A CorbeekRadboud University Medical Center, Department of Medical Biosciences, Nijmegen, the Netherlands.ORCID http://orcid.org/0009-0007-3475-4360
Miranda van BerkelRadboud University Medical Center, Department of Laboratory Medicine, Nijmegen, the Netherlands.ORCID http://orcid.org/0000-0002-6500-3419
Christine Ten HoveRijnstate Hospital, Department of Pediatrics, Arnhem, the Netherlands.ORCID http://orcid.org/0000-0001-9835-5878
Petra A van Setten *Radboud University Medical Center, Amalia Children's Hospital, Department of Pediatric Endocrinology, Nijmegen, the Netherlands. petra.vansetten@radboudumc.nl.ORCID http://orcid.org/0000-0001-5957-9182
Joost G J Hoenderop *Radboud University Medical Center, Department of Medical Biosciences, Nijmegen, the Netherlands. joost.hoenderop@radboudumc.nl.ORCID http://orcid.org/0000-0002-1816-8544

Funding

Health~Holland HH20002968
6 · The paper itself

Abstract

backgroundUrine collection from neonates and infants is challenging. All available urine collection methods (UCMs) have their disadvantages, like invasiveness, contamination, and/or inaccurate measurements of urinary components. This study aimed to demonstrate the accuracy of measurements of urinary components for the novel non-invasive 'Specturi urine collector device'.

methodsThe urine collection textile was incubated under different conditions (incubation duration, temperature, and humidity) with either artificial or human urine. Concentrations of urinary components were compared before and after incubation. Because of suspected crystal formation, the effect of acidification was assessed in combination with crystal analysis.

resultsUrinary concentrations of calcium, magnesium, phosphate, sodium, creatinine, and protein, and pH were accurately measured, except for the calcium concentration in alkaline urines. The incubation conditions showed no to a small effect on the measurement of urinary components, which does not affect clinical decision-making. Crystals containing calcium, magnesium, and phosphorus formed on the textile after incubation with alkaline urine. Acidification recovered the calcium concentration in these urines.

conclusionThe non-invasive 'Specturi urine collector device' provides accurate measurements of urinary components under different conditions. This UCM is more accurate than other textile-based UCMs. Eventually, this device can be used as an accurate as well as patient- and staff-friendly UCM. IMPACT: All urine collection methods for neonates and pre-continent infants have their disadvantages, and textile-based urine collection methods provide inaccurate measurements of urinary components. Furthermore, the effect of changing environmental conditions on measurements of urinary components is unknown for these urine collection methods. This study introduces the 'Specturi urine collector device', a novel non-invasive urine collection device. This device provides accurate measurements for different urinary components under different conditions, like incubation duration, temperature, and humidity. The results show that the 'Specturi urine collector device' has the potential to become an alternative non-invasive urine collection method that is accurate, and patient- and staff-friendly.

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.