Evidence map›Paper›PMID 41975047›Full record

ArticlePediatric nephrology (Berlin, Germany)2026

Pediatric kidney transplantation using donors after circulatory death: a national experience from Spain.

María Herrero-Goñi, Mireia Aguirre Meñica, Alejandro Zarauza Santoveña, Victor Perez-Beltran, Yolanda Calzada, David Canalejo González, Ana Adell Sales, Olalla Alvarez Blanco, Iñaki Bilbao-Villasante, Spanish Pediatric Registry of Renal Replacement Treatment (REPIR I)

Abstract readMulticenter Study
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

María Herrero-GoñiDepartment of Pediatric Nephrology, IIS BioBizkaia Health Research Institute, Cruces University Hospital, University of Deusto, University of the Basque Country UPV/EHU, Cruces Place, 48903, Barakaldo, Bizkaia, Spain. mherrero901@ikasle.ehu.eus.ORCID http://orcid.org/0000-0001-6501-0830
Mireia Aguirre MeñicaDepartment of Pediatric Nephrology, IIS BioBizkaia Health Research Institute, Cruces University Hospital, Barakaldo, Bizkaia, Spain.ORCID http://orcid.org/0009-0009-8955-087X
Alejandro Zarauza SantoveñaDepartment of Pediatric Nephrology, La Paz University Hospital, Madrid, Spain.ORCID http://orcid.org/0000-0002-9415-8911
Victor Perez-BeltranDepartment of Pediatric Nephrology, University Hospital Vall d'Hebron, Barcelona, Spain.ORCID http://orcid.org/0000-0002-9297-371X
Yolanda CalzadaDepartment of Pediatric Nephrology, Sant Joan de Déu Hospital, Barcelona, Spain.ORCID http://orcid.org/0000-0002-0635-4200
David Canalejo GonzálezDepartment of Pediatric Nephrology, Virgen del Rocío University Hospital, Sevilla, Spain.ORCID http://orcid.org/0009-0008-2301-8445
Ana Adell SalesDepartment of Pediatric Nephrology, La Fe University and Polytechnic Hospital, Valencia, Spain.
Olalla Alvarez BlancoDepartment of Pediatric Nephrology, Gregorio Marañón Hospital, Madrid, Spain.ORCID http://orcid.org/0000-0003-2703-6559
Iñaki Bilbao-VillasanteDepartment of Anesthesiology and Intensive Care, Department of Transplantation, Regional Transplant Coordination, Cruces University Hospital, Barakaldo, Bizkaia, Spain.ORCID http://orcid.org/0009-0002-6944-4622
Spanish Pediatric Registry of Renal Replacement Treatment (REPIR I)

Funding

Biocruces Bizkaia es el Instituto de Investigación Sanitaria BB/I/LIB/24/021Instituto de Salud Carlos III PI24/00704
6 · The paper itself

Abstract

backgroundThe shortage of pediatric kidney donors has increased interest in donation after circulatory death (DCD) as an alternative for transplantation.

methodsThis multicenter, retrospective study analyzed all pediatric kidney transplants (KT) from DCD donors performed in Spain between 2013 and 2024 in recipients under 18 years and compared them with 490 KTs from donation after brain death (DBD) donors during the same period.

resultsSixty-four DCD KTs were included. Delayed graft function (DGF) occurred in 12% of cases. DGF risk was higher with donor age > 40 years (p > 0.05) and in grafts retrieved using the rapid recovery (RR) extraction technique (p < 0.05). The median functional warm ischemia time was 13 min (IQR:9-18) and was not associated with an increased risk of DGF. The median cold ischemia time (CIT) was 12.8 h (IQR:9.4-17), and longer CIT was associated with a nonsignificant increase in DGF risk. No DGF occurred when CIT was < 14 h and no additional risk factors were present. Recipients with DGF had a lower estimated glomerular filtration rate one month post-transplant (p < 0.05), but no significant difference at one year. Five-year graft survival rates were not significantly lower in DCD compared to DBD KTs (89.7% vs. 88.5%).

conclusionsAlthough DGF risk was associated with older donor age, RR technique, and longer ischemia times, it did not affect one-year graft function. Graft survival with DCD donors did not appear inferior to that with DBD. DCD KT appears feasible in pediatric recipients and may help expand donor availability under carefully selected conditions.

Indexed as

Delayed Graft FunctionDonor SelectionKidney TransplantationTissue and Organ ProcurementTissue DonorsAdolescentBrain DeathChildChild, PreschoolCold IschemiaFemaleGraft SurvivalHumansInfantMaleRetrospective StudiesDelayed graft functionDonation after brain deathDonation after circulatory deathKidney transplantPediatrics

Identifiers

PMID41975047
PMCPMC13424223

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.