ReviewNature reviews. Chemistry2026
Light-responsive DNA nanostructures.
Review in Nature reviews. Chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
DNA is ideally suited for designing dynamic nanostructures that are reconfigured by external stimuli. One of these stimuli - light - has been used to control DNA nanostructures by the incorporation of light-responsive linkers into DNA strands. Light responsiveness adds to the already rich repertoire of functional properties of DNA nanostructures, including homogenous size, biocompatibility and programmability. Developments in the chemical synthesis of various light-responsive moieties and their incorporation into oligonucleotides have helped to create a library of DNA nanostructures with controlled reconfiguration, high thermal stability, enhanced nuclease resistance and triggered detachment of guest molecules. With these light-responsive features, DNA nanostructures are useful in applications such as diagnostics, drug delivery, data storage, plasmonics and site-directed reactions. In this Review, we discuss the emerging research trends in light-responsive DNA nanostructures, with specific focus on the types of light-responsive functional groups available for incorporation into DNA, strategies used to design and construct light-responsive DNA nanostructures, and their applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.