Evidence map›Paper›PMID 41974934›Full record

GuidelineUrologie (Heidelberg, Germany)2026

[Update of the S2k guideline on the diagnosis and treatment of interstitial cystitis/bladder pain syndrome (IC/BPS)].

Pia V Zimmermann, Andreas Gonsior, Winfried Vahlensieck, Daniela Schultz-Lampel, Andreas Wiedemann, Björn T Kaftan

Abstract readEnglish AbstractPractice Guideline
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In one paragraph

Guideline in Urologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Pia V ZimmermannZentrum für Interstitielle Zystitis und Beckenschmerz, Klinikum Lüneburg, Bögelstraße 1, 21339, Lüneburg, Deutschland. PiaVictoria.Zimmermann@klinikum-lueneburg.de.
Andreas GonsiorKontinenzzentrum, Universitätsklinikum Leipzig, Liebigstraße 20, 04103, Leipzig, Deutschland.
Winfried VahlensieckKlinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Justus-Liebig-Universität Gießen, Rudolf-Buchheim-Str. 7, 35392, Gießen, Deutschland.
Daniela Schultz-LampelKontinenzzentrum Südwest, Schwarzwald-Baar Klinikum, Sonnhaldenstraße 2, 78166, Donaueschingen, Deutschland.
Andreas WiedemannKlinik für Urologie, Ev. Krankenhaus Witten, Pferdebachstraße 27, 58455, Witten, Deutschland.
Björn T KaftanZentrum für Interstitielle Zystitis und Beckenschmerz, Klinikum Lüneburg, Bögelstraße 1, 21339, Lüneburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn July 2025, the S2k guideline on the diagnosis and treatment of interstitial cystitis/bladder pain syndrome (IC/BPS), developed under the auspices of the German Society of Urology (DGU), was published via the Association of the Scientific Medical Societies in Germany (AWMF) following comprehensive revision. The update aimed to improve diagnostic and therapeutic clarity and clinical applicability.

objectiveThis article summarizes the key updates of the revised guideline and provides practical guidance for the clinical management of patients with IC/BPS.

resultsMajor revisions include an updated definition and classification of IC/BPS in accordance with the WHO ICD-11 framework and an expanded overview of current pathogenetic concepts. A clearly structured, multimodal treatment algorithm has been implemented, integrating pharmacological, intravesical, interventional, neuromodulatory, and nonpharmacological therapies. Particular focus is placed on psychosocial comorbidities, individualized dietary management, pelvic floor physiotherapy, pain medicine, and urological rehabilitation.

conclusionThe updated S2k guideline provides an evidence-informed, interdisciplinary, and clinically applicable framework for the management of IC/BPS. Careful diagnostic evaluation and individualized multimodal treatment strategies are essential to improve symptom control and long-term quality of life in affected patients.

Indexed as

Cystitis, InterstitialCombined Modality TherapyGermanyHumansBladder pain syndromeCombination therapyGlomerulationsHunner’s ulcersUrinary urgency

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.