ArticleMicrosystems & nanoengineering2026
Multifunctional bilayer radiative cooling dressing for regenerative wound healing under heat stress.
Article in Microsystems & nanoengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing is influenced by local temperature. Sunlight-induced heating elevates wound temperature, which in turn exacerbates inflammation and infection risks, ultimately delaying regeneration. Despite this critical challenge, current dressings lack any capability for thermal protection. We present a bilayer radiative cooling dressing designed for passive cooling, antibacterial, and antioxidative protection. The top radiative cooling layer is a polyvinyl alcohol matrix with silicon dioxide nanoparticles and eugenol, while the bottom layer contains C-phycocyanin, a natural antioxidant and antibacterial agent. This dressing achieved a solar reflectance of 0.92 (0.3-2.5 μm) and thermal emissivity of 0.92 (8-13 μm), allowing effective heat dissipation. Under outdoor conditions, it maintained surface temperatures up to 15.2 °C below ambient. In a murine full-thickness wound model exposed to simulated sunlight, the dressing suppressed excessive heating (<40 °C) and enhanced repair, achieving 90 ± 2% wound contraction, nearly twice that of a commercial adhesive bandage (47.97 ± 3.45%). These findings integrate passive radiative cooling with antioxidative and antibacterial agent delivery, offering thermal protection and accelerated regenerative healing under heat stress conditions.
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Registered trials
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