Evidence map›Paper›PMID 41974648›Full record

ArticleIntegrative cancer therapies

Chinese Herbal Medicine Is Associated With Improved Survival in Patients With Advanced Lung Cancer Receiving Standard Treatment: A Nationwide Population-Based Propensity Score Matching Study.

Kai-Yuan Hsiao, Wei-Shan Chang, Shi-Chen Ou, Hao-Ren Yao, Der-Chen Chang, Ben-Chang Shia, Ming-Chih Chen, Meng-Che Hsieh

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Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Kai-Yuan HsiaoArtificial Intelligence Development Center, Fu Jen Catholic University, New Taipei City, Taiwan.
Wei-Shan ChangDepartment of Finance and Banking, Shih Chien University, Taipei City, Taiwan.
Shi-Chen OuDepartment of Chinese Medicine, China Medical University Hospital, Taichung city, Taiwan.
Hao-Ren YaoNational Institute of Health, Bethesda, MD, USA.
Der-Chen ChangDepartment of Mathematics and Statistics, Georgetown University, Washington DC, USA.
Ben-Chang ShiaArtificial Intelligence Development Center, Fu Jen Catholic University, New Taipei City, Taiwan.
Ming-Chih ChenArtificial Intelligence Development Center, Fu Jen Catholic University, New Taipei City, Taiwan.
Meng-Che HsiehCollege of Medicine, I-Shou University, Kaohsiung city, Taiwan.ORCID 0000-0002-1626-3396

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a lack of large-scale evidence regarding the prognostic impact of Chinese herbal medicine (CHM) on patients with lung cancer. This paper aimed to conduct a nationwide population-based study to investigate the role of CHM for patients with lung cancer with standard treatment.

methodsPatients diagnosed with lung cancer and treated with standard therapy between 2013 and 2015 were retrospectively identified from National Health Insurance Research Database and Taiwan Cancer Registry. Patients were classified into a CHM group and a non-CHM group based on prior medical records. Kaplan-Meier analysis was performed to estimate overall survival (OS) between each group.

resultsA total of 7351 matched patients were included in the outcome analysis and comparison, with 3677 patients in the CHM cohort and 3674 patients in the non-CHM cohort. The mean age of our patients was 60.68 ± 11.26 years, and 56% of our patients were female. Our results demonstrates that patients who received CHM had significantly longer OS compared to those who did not receive CHM (HR: 0.59, 95% CI: 0.556-0.625,

conclusionOur nationwide population-based study suggested that CHM in conjugation with standard treatment was associated with improved survival in patients with advanced lung cancer. Integrating cancer treatment with CHM could be adopted in the treatment of lung cancer to improve prognosis.

Indexed as

Drugs, Chinese HerbalLung NeoplasmsAgedFemaleHumansKaplan-Meier EstimateMaleMedicine, Chinese TraditionalMiddle AgedPrognosisPropensity ScoreRetrospective StudiesTaiwanDrugs, Chinese Herbaladvanced stageChinese herbal medicinelung cancerprognosissurvival

Identifiers

PMID41974648
PMCPMC13080189

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.