Evidence map›Paper›PMID 41974632›Full record

ArticleJournal of applied toxicology : JAT2026

Beryllium Sulfate-Induced Cellular Senescence via the IL-6/STAT3 Pathway to Promote Pulmonary Fibrosis.

Yanping Lu, Yaqi Li, Yuqi Tong, Lian Huang, Zhaohui Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied toxicology : JAT, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanping LuDepartment of Preventive Medicine, School of Public Health, Hengyang Medical School, University of South China, Hengyang, China.
Yaqi LiDepartment of Preventive Medicine, School of Public Health, Hengyang Medical School, University of South China, Hengyang, China.
Yuqi TongDepartment of Preventive Medicine, School of Public Health, Hengyang Medical School, University of South China, Hengyang, China.
Lian HuangDepartment of Preventive Medicine, School of Public Health, Hengyang Medical School, University of South China, Hengyang, China.
Zhaohui ZhangDepartment of Preventive Medicine, School of Public Health, Hengyang Medical School, University of South China, Hengyang, China.ORCID 0000-0002-6104-2197

Funding

Natural Science Foundation of Hunan Province 2026JJ50554Science Research Key Project of Education Department of Hunan Province 23A0343
6 · The paper itself

Abstract

Beryllium is widely used in nuclear technology, aerospace, and defense. Long-term beryllium exposure causes chronic beryllium disease (CBD) characterized predominantly by pulmonary fibrosis. Cellular senescence is an important mechanism underlying pulmonary fibrosis, and the IL-6/STAT3 pathway has been implicated as a central axis linking inflammation, senescence, and tissue remodeling. However, whether this pathway promotes beryllium sulfate (BeSO

Indexed as

BerylliumCellular SenescenceInterleukin-6Pulmonary FibrosisSTAT3 Transcription FactorA549 CellsAnimalsHumansLungMaleRatsRats, Sprague-DawleySignal TransductionBerylliumberyllium sulfateIl6 protein, ratInterleukin-6Stat3 protein, ratSTAT3 Transcription Factorberyllium sulfatecellular senescenceIL‐6/STAT3 pathwaypulmonary fibrosis

Identifiers

PMID41974632
PMCPMC13532936

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.