Recent Updates to Diagnosis and Treatment of Spontaneous Intracranial Hypotension.

Ajay A Madhavan, Edward S Yoon, J Levi Chazen

Abstract readReviewCase Reports

In one paragraph

Review in Korean journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

When headache meets visual disturbance: An evidence-based review of common and critical entities.Science progress
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ajay A MadhavanDepartment of Radiology, Duke University, Durham, NC, USA. ajay.madhavan@duke.edu.ORCID https://orcid.org/0000-0003-1794-4502

Edward S YoonDepartment of Radiology, Hospital for Special Surgery, New York, NY, USA.ORCID https://orcid.org/0000-0002-3548-7133

J Levi ChazenDepartment of Radiology, Hospital for Special Surgery, New York, NY, USA.ORCID https://orcid.org/0000-0002-6146-2191

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous intracranial hypotension is a neurologic condition that is caused by a spinal cerebrospinal fluid (CSF) leak. The resulting CSF hypovolemia can manifest as a variety of clinical symptoms, with orthostatic headache being the most common. Although this disease has been recognized for decades, modern understanding of the types of causative spinal CSF leaks, diagnostic imaging tests to localize these leaks, and treatment options has evolved substantially in recent years. In this focused review article, we will provide an overview of the current diagnosis and treatment of spontaneous intracranial hypotension. We will emphasize recent improvements in understanding the pathophysiology of spinal leaks, developments in myelographic techniques to localize CSF leaks, and new treatment options for each type of leak.

Indexed as

Intracranial HypotensionCerebrospinal Fluid LeakHumansMyelographyTomography, X-Ray ComputedCSF leakCSF-venous fistulaPhoton counting CT myelogramSpontaneous intracranial hypotension

Identifiers

PMID41974534

DOI10.3348/kjr.2026.0064

PMCPMC13136579

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.