Evidence map›Paper›PMID 41973926›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Industrialization increases the estrogen-recycling capacity of the gut microbiome.

Rebecca S A Brittain, Richard G Bribiescas, Grazyna Jasienska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rebecca S A BrittainDepartment of Anthropology, Yale University, New Haven, CT 06520.ORCID 0000-0002-5482-369X
Richard G BribiescasDepartment of Anthropology, Yale University, New Haven, CT 06520.ORCID 0000-0002-8228-307X
Grazyna JasienskaDepartment of Environmental Health, Faculty of Health Sciences, Jagiellonian University Medical College, Kraków 31-066, Poland.ORCID 0000-0001-8716-6342

Funding

National Science Foundation (NSF) 2313905
6 · The paper itself

Abstract

Estrogens influence many aspects of human physiology and health, including fertility, growth, metabolic function, and susceptibility to disease. Up to 65% of circulating estrogens are excreted into the gut via bile, but only 10-15% are eliminated in feces, indicating substantial estrogen reabsorption [H. Adlercreutz and P. Järvenpää,

Indexed as

EstrogensGastrointestinal MicrobiomeFecesFemaleHumansEstrogensestrobolomeestrogen metabolismgut microbiomeindustrialized microbiome

Identifiers

PMID41973926
PMCPMC13099636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.