Evidence map›Paper›PMID 41973913›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Alternative splicing of the

Chunjiao Sun, Jingshuang Zhao, Nana Li, Xuebo Yao, Yanfei Wang, Chul Hoon Kim, Jinwoong Bok, Anthony W Peng, Zhigang Xu

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunjiao SunShandong Provincial Key Laboratory of Development and Regeneration and Key Laboratory for Experimental Teratology of the Ministry of Education, School of Life Sciences, Shandong University, Qingdao 266237, Shandong, China.ORCID 0009-0006-3997-0022
Jingshuang ZhaoShandong Provincial Key Laboratory of Development and Regeneration and Key Laboratory for Experimental Teratology of the Ministry of Education, School of Life Sciences, Shandong University, Qingdao 266237, Shandong, China.ORCID 0009-0009-3116-5848
Nana LiShandong Provincial Key Laboratory of Development and Regeneration and Key Laboratory for Experimental Teratology of the Ministry of Education, School of Life Sciences, Shandong University, Qingdao 266237, Shandong, China.
Xuebo YaoShandong Provincial Key Laboratory of Development and Regeneration and Key Laboratory for Experimental Teratology of the Ministry of Education, School of Life Sciences, Shandong University, Qingdao 266237, Shandong, China.ORCID 0000-0003-4084-1456
Yanfei WangShandong Provincial Key Laboratory of Development and Regeneration and Key Laboratory for Experimental Teratology of the Ministry of Education, School of Life Sciences, Shandong University, Qingdao 266237, Shandong, China.
Chul Hoon KimDepartment of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-7360-429X
Jinwoong BokDepartment of Anatomy, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0003-1958-1872
Anthony W PengDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.ORCID 0000-0002-2208-6779
Zhigang XuShandong Provincial Key Laboratory of Development and Regeneration and Key Laboratory for Experimental Teratology of the Ministry of Education, School of Life Sciences, Shandong University, Qingdao 266237, Shandong, China.ORCID 0000-0003-0082-7297

Funding

MOST | National Key Research and Development Program of China (NKPs) 2022YFE0131900 2024YFC2511104MOST | National Natural Science Foundation of China (NSFC) 82192861
6 · The paper itself

Abstract

Cochlear hair cells are the mechanosensitive receptor cells responsible for detecting sound information. They are characterized by their apical F-actin-filled stereocilia that are essential for mechano-electrical transduction. Previously, we and other groups reported that RNA Binding Motif Protein 24 (RBM24) plays pivotal roles in stereocilia development and maintenance by regulating pre-mRNA alternative splicing and mRNA stability. In the present work, we show that exon 4 of the mouse

Indexed as

Alternative SplicingHair Cells, AuditoryHearingRNA-Binding ProteinsStereociliaAnimalsExonsHearing LossMiceMice, KnockoutProtein IsoformsRNA, MessengerProtein IsoformsRbm24 protein, mouseRNA-Binding ProteinsRNA, Messengeralternative splicinghair cellsinner earRBM24stereocilia

Identifiers

PMID41973913
PMCPMC13099659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.