ArticleJACC. Case reports2026
Epicardial Fat Necrosis as a Rare Cause of Chest Pain: Peeling Back the Layers.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpicardial fat necrosis (EFN) is a rare, self-limiting condition that presents as acute severe chest pain. Symptoms can mimic life-threatening conditions (myocardial infarction, pulmonary embolism, and pericarditis). CASES SUMMARY: We present 2 cases of EFN with acute, left-sided pleuritic chest pain without a clear precipitating factor. Blood work revealed elevated D-dimer, C-reactive protein, and normal troponin. Chest computed tomography (CT) scan showed characteristic EFN appearance. They were managed with nonsteroidal anti-inflammatory drugs with clinical and imaging resolution. DISCUSSION: Our cases illustrate typical examples of EFN in presenting with acute, left-sided pleuritic chest pain. Pathogenesis is unknown; incidence is around 0.26% among patients undergoing chest CT in the emergency department. CT ± cardiac magnetic resonance imaging are crucial in diagnosing the condition. Management is typically conservative, with pharmacological treatment preferred over surgical excision. TAKE-HOME MESSAGES: EFN is a rare, benign cause of acute chest pain in the emergency department. Diagnosis is typically made with CT and/or cardiac magnetic resonance imaging, and management is generally conservative.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.