Evidence map›Paper›PMID 41973884›Full record

ArticleJACC. Case reports2026

Concurrent Patent Foramen Ovale and Pulmonary Arteriovenous Malformation Etiology: Complex Case of Cryptogenic Stroke.

Abdullah Al Qaraghuli, Kalyan R Chitturi, Beni Rai Verma, Jason Galo, Itsik Ben-Dor, Toby Rogers, Ron Waksman, Lowell F Satler, Michael C Slack

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdullah Al QaraghuliDepartment of Internal Medicine, MedStar Washington Hospital Center, Washington, DC, USA.
Kalyan R ChitturiSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Beni Rai VermaSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Jason GaloSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Itsik Ben-DorSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Toby RogersSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA; Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Ron WaksmanSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA. Electronic address: ron.waksman@medstar.net.
Lowell F SatlerSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
Michael C SlackSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatent foramen ovale (PFO) and pulmonary arteriovenous malformations (PAVMs) are congenital vascular abnormalities that can lead to right-to-left shunting, potentially causing paradoxical embolism. CASE SUMMARY: We describe a case of a 39-year-old woman who presented with syncope and left-sided facial numbness; her brain imaging confirmed a subacute lacunar infarct in the left thalamus. A transthoracic echocardiogram showed a PFO with moderate to severe right-to-left shunting. The patient underwent successful PFO closure. Postprocedurally, she developed transient hypotension. Computed tomography of the chest, abdomen, and pelvis was performed to exclude bleeding. Incidentally, a PAVM in the right middle lobe of the lung was identified, which was then successfully closed with embolization. DISCUSSION: PFO is a well-established cause of paradoxical embolism, but rarer extracardiac shunts such as PAVMs can coexist and contribute to cryptogenic stroke. TAKE-HOME MESSAGE: A comprehensive evaluation for multiple shunt sources is essential in younger patients with cryptogenic stroke.

Indexed as

congenital heart defectpercutaneous coronary interventionstroke

Identifiers

PMID41973884
PMCPMC13221795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.