Evidence map›Paper›PMID 41973630›Full record

ArticleJMIR medical education2026

Developing and Validating a Coding Scheme for Clinical Reasoning in History Taking Using Generative AI-Based Virtual Patients: Systematic Text Condensation Approach.

Naping Chen, Luzhen Tang, Yang Liu, Changmin Lin, Zijian Li, Chujun Shi, Mengyu Xia, Dragan Gasevic, Danijela Gasevic, Jinbin Zheng and 2 more

Abstract read
In one paragraph

Article in JMIR medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Naping ChenDepartment of Clinical Skills Training Center, Shantou University Medical College, Shantou, Guangdong, China.ORCID 0000-0002-3996-5454
Luzhen TangGraduate School of Education, Peking University, 5th Yiheyuan Road, Beijing, 100871, China, 86 15210167528.ORCID 0009-0005-0102-5677
Yang LiuDepartment of Clinical Skills Training Center, Shantou University Medical College, Shantou, Guangdong, China.ORCID 0009-0005-3818-2967
Changmin LinOffice of Teaching Affairs, Shantou University Medical College, Shantou, Guangdong, China.ORCID 0009-0000-8880-8423
Zijian LiGraduate School of Education, Peking University, 5th Yiheyuan Road, Beijing, 100871, China, 86 15210167528.ORCID 0009-0000-0566-9051
Chujun ShiDepartment of Clinical Skills Training Center, Shantou University Medical College, Shantou, Guangdong, China.ORCID 0009-0002-0126-9311
Mengyu XiaGraduate School of Education, Peking University, 5th Yiheyuan Road, Beijing, 100871, China, 86 15210167528.ORCID 0009-0001-8496-8611
Dragan GasevicFaculty of Information Technology, Monash University, 25 Exhibition Walk, Clayton, Melbourne, VIC 3168, Australia.ORCID 0000-0001-9265-1908
Danijela GasevicSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.ORCID 0000-0001-5976-4011
Jinbin ZhengDepartment of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.ORCID 0009-0005-9826-0795
Yizhou Fan *Graduate School of Education, Peking University, 5th Yiheyuan Road, Beijing, 100871, China, 86 15210167528.ORCID 0000-0003-2777-1705
Xinyu Li *Faculty of Information Technology, Monash University, 25 Exhibition Walk, Clayton, Melbourne, VIC 3168, Australia.ORCID 0000-0003-2681-4451

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Effective history taking helps clinicians identify key symptoms and form accurate hypotheses. Generative artificial intelligence (GenAI)-based virtual patients (VPs) are increasingly used to simulate and practice history taking. However, there is currently no straightforward approach to effectively identify students' clinical reasoning activities during these interactions, which limits the ability to provide instructional feedback. Objective: This study aims to develop and validate a coding scheme to identify medical students' history-taking behaviors during interactions with GenAI-based VPs. Methods: Second-year medical students (N=210) participated in 5 history-taking cases with GenAI-based VPs, yielding 1030 dialogues. Researchers applied the systematic text condensation method to these dialogue data from cases 1 to 4 to inductively develop a coding scheme and validate coding consistency. Subsequently, the dialogue data from case 5 were used to assess the correlation between the students' history-taking behaviors and their academic performance, including diagnostic accuracy, history-taking checklist scores, clinical knowledge test scores, and postencounter form scores. Results: A coding scheme comprising 12 behaviors across 3 dimensions-clinical reasoning behaviors, information gathering behaviors, and social interaction behaviors-was developed with high interrater reliability (κ≥0.85). The correlation analysis revealed that key clinical reasoning behaviors, such as summarizing and integrating and logical organization, showed significant positive correlations with multiple performance metrics, underscoring their importance in fostering clinical competence. In contrast, information gathering behaviors such as specifying symptoms and routine question were associated with clinical knowledge and thoroughness of history taking but were less predictive of diagnostic accuracy. Conclusions: This study developed a reliable, theory-informed coding scheme that can identify students' questioning behaviors during history taking with GenAI-based VPs. The scheme effectively captures higher-order cognitive strategies and provides valuable insights into the development of clinical reasoning in medical students. This approach offers a scalable and efficient way to integrate real-time feedback into future medical education, fostering personalized learning and advancing competency-based assessments in clinical training.

Indexed as

Clinical ReasoningMedical History TakingStudents, MedicalClinical CompetenceEducation, Medical, UndergraduateFemaleGenerative Artificial IntelligenceHumansMalePatient Simulationclinical reasoningcoding schemegenerative artificial intelligencehistory takingmedical educationvirtual patients

Identifiers

PMID41973630
PMCPMC13075466

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.