ReviewThe MAK collection for occupational health and safety2025
Aniline - Addendum: Re-evaluation of the BAT value and evaluation of a pregnancy risk group for the BAT value: Assessment Values in Biological Material - Translation of the German version from 2025.
Review in The MAK collection for occupational health and safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
The German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) re-evaluated the data for aniline [62-53-3] to verify the biological tolerance value (BAT value) of 500 μg aniline/l urine and to assign the BAT value to a pregnancy risk group, considering all toxicological end points. Relevant studies were identified from a literature search. The critical effect of aniline exposure in humans is considered to be the formation of methaemoglobin. It must be ensured that the methaemoglobin value remains below 5%, even if the BAT value is maintained. In an experimental study, the methaemoglobin content in human blood rose from 0.72% to an average methaemoglobin value of 1.2% (maximum of 2.07% methaemoglobin) during six hours of exposure to 2 ml aniline/m
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